Variable | Description |
---|---|
Ret i,t | Number of circulating reticulocytes of age i at time t |
RBC i,t | Number of mature red blood cells of age i at time t |
iRBC i,t | Number of infected red blood cells of age i at time t |
rRBC t | Number of RBCs that will die due to random death |
M t | Number of free merozoites at time t |
P t | Hourly production and release of reticulocytes from bone marrow into the blood-stream at time t |
ARR t | Age-class into which reticulocytes are released |
iARR t | Integer part of ARRt |
dARR t | Decimal part of ARRt |
SfRet i,t | Fraction of reticulocytes in age class i at time point t that survive to time point t + 1 |
SfRBC i,t | Fraction of RBCs in age class i at time-point t that survive to time point t + 1 |
SfiRBC i,t | Fraction of infected RBCs in age class i at time point t that survive to time point t + 1 |
ToI | Time point at which an infection starts |
NoI | Number of infected RBCs that start an infection at time point ToI |
RDt | Number of RBCs removed at time point t due to random death |
hf i | Hazard function for RBCs |
RBCInv i,t | Fraction of RBCs in age class i at time point t lost to merozoite invasion |
RetInv i,t | Fraction of reticulocytes in age class i at time point t lost to merozoite invasion |
UR t | Number of RBCs removed by bystander effect |
TRBC t | Total number of RBCs at time t |
TRet t | Total number of reticulocytes at time t |
Ret Pref | Reticulocyte preference over mature RBCs |
RBCAPf i | Merozoite-RBC age preference function |
PiRet | Percentage that a merozoite will infect a reticulocyte |
NiRet | Number of reticulocytes to be infected |
PiRBC i | Probability that a merozoite will infect an RBC of age i |
MerLeft | Number of merozoites left after accounting for invasion of reticulocytes |
NiRBC f | Number of RBCs of age class f to be invaded by a merozoite |