Table 2 Demographic, clinical and laboratory variables of study participants
Variables | Cases (N = 1629) | Control (N = 445) | p-value |
|---|---|---|---|
Demographic | |||
Average age (years) | 2.14 ± 1.57 | 2.45 ± 1.62 | |
Clinical | |||
Temperature (mean ± SD) (°C) | 37.9 ± 1.3 | 36.9 ± 0.5 | |
Pallor (%) | 48 | 3 | |
Convulsing (%) | 9 | – | |
Vomiting (%) | 32 | – | |
Laboratory | Mean ± SD | Mean ± SD | |
Haemoglobin (g/dL) | 9.78 ± 2.4 | 11.95 ± 0.14 | 0.45 |
TWBC (× 109/L) | 7.77 ± 3.02 | 8.26 ± 3.40 | 0.58 |
Median (IQR) | Median (IQR) | ||
Monocytes (× 109/L) | 0.60 (0.40–0.90) | 0.40 (0.24–0.73) | 0.0095* |
Lymphocytes (× 109/L) | 1.91 (1.38–3.26) | 3.42 (2.09–5.90) | < 0.0001 * |
Neutrophils (× 109/L) | 4.53 (2.21–6.38) | 3.41 (2.50–5.02) | 0.2622 |
M:L ratio | 0.31 (0.17–0.44) | 0.11 (0.07–0.24) | < 0.0001* |
N:L ratio | 1.93 (0.82–3.63) | 1.07 (0.59–1.87) | 0.0011* |
M:N ratio | 0.14 (0.08–0.29) | 0.12 (0.07–0.17) | 0.113 |
Parasitaemia (/µL) | |||
Uncomplicated malaria | 67, 317 (32,647–81,367) | ||
Severe malaria | 112, 513 (109,801–143,246) | ||