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Table 3 Haematological parameters of study participants according to age group

From: Correlation of malaria parasitaemia with peripheral blood monocyte to lymphocyte ratio as indicator of susceptibility to severe malaria in Ghanaian children

Age group

Haematological parameter

Cases

Control

p-value

Mean ± SD

Mean ± SD

0–3

Haemoglobin (g/dL)

9.55 ± 2.57

10.56 ± 1.45

0.43

TWBC (× 109/L)

8.93 ± 3.01

8.85 ± 3.17

0.81

 

Median (IQR)

Median (IQR)

 

Monocytes (× 109/L)

0.60 (0.40–1.00)

0.36 (0.21–0.84)

0.0175*

Lymphocytes (× 109/L)

2.72 (1.70–3.70)

3.70 (2.85–6.84)

0.0059*

Neutrophils (× 109/L)

5.50 (3.00–7.10)

3.34 (2.61–4.61)

0.0933

M:L ratio

0.27 (0.13–0.39)

0.10 (0.06 –0.17)

0.0001*

N:L ratio

1.73 (0.91–3.56)

1.05 (0.47–1.61)

0.0087*

M:N ratio

0.15 (0.09–0.21)

0.11 (0.05–0.17)

0.1949

4–5

 

Mean ± SD

Mean ± SD

 

Haemoglobin (g/dL)

10.12 ± 2.06

11.30 ± 1.80

0.02*

TWBC (× 109/L)

7.74 ± 2.66

7.30 ± 3.66

0.66

 

Median (IQR)

Median (IQR)

 

Monocytes (× 109/L)

0.60 (0.30–0.82)

0.43 (0.28–0.71)

0.2254

Lymphocytes (× 109/L)

1.69 (1.30–2.39)

2.16 (1.47–4.95)

0.0345*

Neutrophils (× 109/L)

3.23 (1.87–5.60)

3.37 (2.24–5.20)

0.9773

M:L ratio

0.38 (0.21–0.46)

0.14 (0.08–0.29)

0.0008*

N:L ratio

2.24 (0.74–3.93)

1.26 (0.99–2.00)

0.0851

M:N ratio

0.14 (0.07–0.37)

0.12 (0.07–0.17)

0.4145

  1. * Significant at p ≤ 0.05