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Table 3 Proteins with differential levels observed between severe cases that presented with febrile convulsions compared to cerebral malaria

From: Levels of human proteins in plasma associated with acute paediatric malaria

Primary biological process Gene Uniprot ID Gene description p-value Antibody
Erythrocyte morphology ANK1 P16157 Ankyrin 1 1e−02 HPA004842
MPP1 Q00013 Membrane palmitoylated protein 1 1e−03 HPA076675
Acute phase response CD14 P08571 CD14 molecule 4e−03 HPA001887+
Cell cycle regulation CDK14 O94921 Cyclin dependent kinase 14 3e−03 HPA015267
ECM disassembly ELANE P08246 Neutrophil elastase 4e−03 MAB91671 R&D+
  1. Information about the five proteins showing differential levels in patients with febrile convulsions compared to cerebral malaria, grouped on primary biological function, and unadjusted p-values based on Wilcoxon rank-sum test. All five proteins showed increased levels in patients with febrile convulsions compared to cerebral malaria. Proteins supported by multiple antibodies are marked + in the antibody column (see also Additional files 5, 12)