Within-population genetic diversity and population structure of Plasmodium knowlesi merozoite surface protein 1 gene from geographically distinct regions of Malaysia and Thailand

Table 2 Location wise nucleotide diversity, natural selection, haplotype diversity and neutrality indices of pkmsp1-₄₂

Location	No. of samples	SNPs	No. haplotype	Diversity ± SD		dN–dS	Codon based z test	Taj D	Fu and Li’s D*	Fu and Li’s F*
Location	No. of samples	SNPs	No. haplotype	Haplotype	Nucleotide	dN–dS	Codon based z test	Taj D	Fu and Li’s D*	Fu and Li’s F*
Malaysian Borneo (Sarawak)	37	39	32	0.989 ± 0.010	0.006 ± 0.0006	− 4.27	P < 0.000	− 1.07	− 1.22	− 1.33
Malaysian Borneo (Sabah)	5	20	5	1.0 ± 0.126	0.009 ± 0.002	− 3.75	P < 0.000	− 0.61	− 0.61	− 0.66
Peninsular Malaysia	11	28	9	0.978 ± 0.054	0.010 ± 0.001	− 3.10	P < 0.002	− 0.27	− 0.08	− 0.14
Thailand	23	38	14	0.937 ± 0.033	0.010 ± 0.001	− 3.21	P < 0.001	− 0.08	− 0.35	− 0.31
Overall	76	72	58	0.990 ± 0.005	0.009 ± 0.0005	− 4.48	P < 0.000	− 1.29	− 2.54**	− 2.45**

ISSN: 1475-2875