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Table 1 Study profile of index cases and FTAT investigation, by transmission and importation category

From: Malaria case investigation with reactive focal testing and treatment: operational feasibility and lessons learned from low and moderate transmission areas in Amhara Region, Ethiopia

  Low transmission, low importation villages
6 villages: Ancharo, Choresa, Dehina Sositu, Hardibo, Ketie, Zengoba Denguma
Low transmission, high importation villages
3 villages: Berhan Chora*; Enashenifalen; Yeginid Lomi
High transmission, low importation village
1 village: Kumar
Aftit*
Total
10 villages
2015 population estimates 34,294 23,684 3666 61,644
 Index cases
  Passively detected P. falciparum/mixed, n 23 156 228 407
  Investigated, n (%) 18 (78.3) 141 (90.4) 61 (26.8) 220 (54.1)
  Investigated cases with travel history in past 30 days, n (%) 2 (11) 126 (89.4) 0 (0) 128 (58.2)
  Investigated cases with no travel history in past 30 days, n (%) 16 (89.0) 15 (10.6) 61 (100.0) 92 (41.8)
  Interval parasite index (per 1000 population in the high transmission season) 0.67 6.6 62.2 6.6
FTAT investigation
 Index case HH
  Individuals in HHs, n (excluding index cases) 74 529 270 873
  Individuals tested, n (%) 66 (89.2) 503 (95.1) 203 (75.2) 772 (88.4)
  RDT positivity, n (%) 5 (7.6) 7 (1.4) 25 (12.3) 37 (4.8)
 Neighbouring HH
  HHs visited, n 112 254 328 694
  Individuals in HHs, n 529 1113 1341 2983
  Individuals tested, n (%) 467 (88.3) 1002 (90.0) 1002 (74.7) 2471 (82.8)
  RDT positivity, n (%) 2 (0.4)** 8 (0.8) 80 (8.0)** 90 (3.6)
  1. FTAT, focal test and treat; HH, household
  2. * In Berhan Chora and Kumer Aftit, the FTAT procedures were modified on 1 November, 2014 because it was not possible to complete case investigations for every index case. If the index case had a travel history, only the index case household was visited for the case investigation rather than the index case household plus up to 10 neighbouring households
  3. ** Significant P value comparing RDT positivity in Index HH and Neighbouring HH (P < 0.05)