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Table 1 Number of cases with each pfdhfr genotype allele* from different districts in Indonesia in two study periods

From: Origins and spread of novel genetic variants of sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates in Indonesia

Place n**
(mixed cases)
2004–2006
Island Province District ANCSI ANCNI ANRNI ANRNL
Sumatera Riau Indragiri Hilir 6    6  
Kalimantan East Kalimantan Paser 34    29 5
    (2)    (2a)/2 (2a)/2
Java East Java Pacitan 29    19 10
Lombok West Nusa Tenggara West Lombok 45    45  
Sumbawa West Nusa Tenggara Sumbawa 78 1 5 72  
    (2) (2a)/2   (2a)/2  
Papua Papua Jayapura 9    9  
    201 1 5 180 15
    (4) (2)/2   (4)/2 (2)/2
Place n**
(mixed cases)
2009–2012
Island Province District ANCSI ANCNI ANRNI ANRNL
Sumatera Riau Indragiri Hilir 1    1  
Sumatera Jambi Merangin 1     1
Kalimantan Middle Kalimantan Seruyan 19    1 18
Kalimantan South Kalimantan Banjar 58   2 36 20
    (1)   (1a)/2 (1a)/2  
Lombok West Nusa Tenggara West Lombok 48    48  
Timor East Nusa Tenggara Timor Tengah Selatan 3    3  
Sulawesi Gorontalo Gorontalo 2    2  
Papua Papua Jayapura 46 5   41  
    178 5 2 132 39
    (1)   (1)/2 (1)/2  
  1. * pfdhfr genotype alleles are presented with the amino acids at the position of 16, 51, 59, 108, and 164. The underlined bold type indicates amino acid substitution
  2. ** Number of mixed infection cases are presented in brackets as (N), and each pair of the mixed case is presented with superscript as (Na)/2