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Table 1 Number of cases with each pfdhfr genotype allele* from different districts in Indonesia in two study periods

From: Origins and spread of novel genetic variants of sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates in Indonesia

Place

n**

(mixed cases)

2004–2006

Island

Province

District

ANCSI

ANCNI

ANRNI

ANRNL

Sumatera

Riau

Indragiri Hilir

6

  

6

 

Kalimantan

East Kalimantan

Paser

34

  

29

5

   

(2)

  

(2a)/2

(2a)/2

Java

East Java

Pacitan

29

  

19

10

Lombok

West Nusa Tenggara

West Lombok

45

  

45

 

Sumbawa

West Nusa Tenggara

Sumbawa

78

1

5

72

 
   

(2)

(2a)/2

 

(2a)/2

 

Papua

Papua

Jayapura

9

  

9

 
   

201

1

5

180

15

   

(4)

(2)/2

 

(4)/2

(2)/2

Place

n**

(mixed cases)

2009–2012

Island

Province

District

ANCSI

ANCNI

ANRNI

ANRNL

Sumatera

Riau

Indragiri Hilir

1

  

1

 

Sumatera

Jambi

Merangin

1

   

1

Kalimantan

Middle Kalimantan

Seruyan

19

  

1

18

Kalimantan

South Kalimantan

Banjar

58

 

2

36

20

   

(1)

 

(1a)/2

(1a)/2

 

Lombok

West Nusa Tenggara

West Lombok

48

  

48

 

Timor

East Nusa Tenggara

Timor Tengah Selatan

3

  

3

 

Sulawesi

Gorontalo

Gorontalo

2

  

2

 

Papua

Papua

Jayapura

46

5

 

41

 
   

178

5

2

132

39

   

(1)

 

(1)/2

(1)/2

 
  1. * pfdhfr genotype alleles are presented with the amino acids at the position of 16, 51, 59, 108, and 164. The underlined bold type indicates amino acid substitution
  2. ** Number of mixed infection cases are presented in brackets as (N), and each pair of the mixed case is presented with superscript as (Na)/2