Fig. 1

Representative simulations in regions with differing transmission intensities. Four scenarios are considered. In blue, 80% coverage of SMC in under 5 year olds, with no TCP-6 compound and only SP–AQ; in red 80% coverage of SMC under 10 year olds with no TCP-6 compound and only SP–AQ; in dark blue 80% coverage of SMC and a TCP-6 compound in all children under 5; and in magenta 80% coverage of SMC and a TCP-6 compound in all children under 10. The clinical case incidence of symptomatic malaria on the Y-axis for the left-hand figures is the incidence in children 0–10 years of age. The PCR-measured prevalence on the Y-axis for the right-hand figures is in all age groups