Fig. 4
From: A discovery and development roadmap for new endectocidal transmission-blocking agents in malaria
Screening cascade for identifying compounds for TCP-6 or ATSB. The bottom box identifies the suite of studies necessary for full evaluation of a potential TCP-6 candidate drug. If any properties require optimization, then medicinal chemistry would be driven using the A. stephensi SMFA to assess potency alongside any of the other relevant non-efficacy assays
