Fig. 5
From: A discovery and development roadmap for new endectocidal transmission-blocking agents in malaria
Draft TCP-6 clinical development plan for a novel TCP-6 added to SP–AQ for seasonal malaria chemoprevention in asymptomatic subjects < 10 years of age. *West and Central Africa as required: Burkina Faso, Cameroun, Chad, Gambia, Ghana, Guinea, Guinea Bissau, Niger, Nigeria, Mali, Senegal, Togo; **Excluding women of child-bearing potential; SAD, Single ascending dose study; SMFA, Standard membrane feeding assay; MAD, multiple ascending dose study; SP–AQ, sulfadoxine–pyrimethamine