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Table 1 Genetic diversity of Plasmodium falciparum msp1 and msp2 among age groups of symptomatic patients on Bioko Island, Equatorial Guinea (2011–2014)

From: Genetic diversity and allele frequencies of Plasmodium falciparum msp1 and msp2 in parasite isolates from Bioko Island, Equatorial Guinea

Gene Allelic type Age group (years) Total
< 5 5–19 20–39 ≥ 40
n (%) n (%) n (%) n (%) n (%)
(n = 6) (n = 47) (n = 88) (n = 40) (n = 181)
msp1 K1 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
MAD20 0 (0) 0 (0) 0 (0) 2 (5.0) 2 (1.1)
RO33 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
K1/MAD20 0 (0) 5 (10.6) 28 (31.8) 17 (42.5) 50 (27.6)
K1/RO33 1 (26.7) 0 (0) 1 (1.1) 1 (2.5) 3 (1.7)
MAD20/RO33 0 (0) 1 (0.55) 1 (1.1) 3 (7.5) 5 (2.8)
K1/MAD20/RO33 5 (83.3) 41 (87.2) 55 (62.5) 17 (42.5) 118 (65.2)
Total 6 (100) 47 (100) 85 (96.6) 38 (95) 178 (97.2)
MOI 3.33 3.81 3.59 3.03 3.5
msp2 3D7 1 (26.7) 7 (14.9) 26 (29.5) 14 (35) 48 (26.5)
FC27 1 (26.7) 1 (2.1) 1 (1.1) 1 (2.5) 4 (2.2)
3D7/FC27 4 (66.7) 37 (78.7) 55 (62.5) 25 (62.5) 121 (66.9)
Total 6 (100) 45 (95.7) 82 (93.2) 40 (100) 173 (95.6)
MOI 1.83 2.31 2.01 2.1 2.01
Multiclonal isolates 6 (100) 47 (100) 87 (98.9) 41 (100) 181 (100)
Overall MOI 5.17 6.02 5.53 5.13 5.51
  1. n number of individuals, MOI multiplicity of infection