Table 1 Genetic diversity of Plasmodium falciparum msp1 and msp2 among age groups of symptomatic patients on Bioko Island, Equatorial Guinea (2011–2014)
Gene | Allelic type | Age group (years) | Total | |||
|---|---|---|---|---|---|---|
< 5 | 5–19 | 20–39 | ≥ 40 | |||
n (%) | n (%) | n (%) | n (%) | n (%) | ||
(n = 6) | (n = 47) | (n = 88) | (n = 40) | (n = 181) | ||
msp1 | K1 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
MAD20 | 0 (0) | 0 (0) | 0 (0) | 2 (5.0) | 2 (1.1) | |
RO33 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
K1/MAD20 | 0 (0) | 5 (10.6) | 28 (31.8) | 17 (42.5) | 50 (27.6) | |
K1/RO33 | 1 (26.7) | 0 (0) | 1 (1.1) | 1 (2.5) | 3 (1.7) | |
MAD20/RO33 | 0 (0) | 1 (0.55) | 1 (1.1) | 3 (7.5) | 5 (2.8) | |
K1/MAD20/RO33 | 5 (83.3) | 41 (87.2) | 55 (62.5) | 17 (42.5) | 118 (65.2) | |
Total | 6 (100) | 47 (100) | 85 (96.6) | 38 (95) | 178 (97.2) | |
MOI | 3.33 | 3.81 | 3.59 | 3.03 | 3.5 | |
msp2 | 3D7 | 1 (26.7) | 7 (14.9) | 26 (29.5) | 14 (35) | 48 (26.5) |
FC27 | 1 (26.7) | 1 (2.1) | 1 (1.1) | 1 (2.5) | 4 (2.2) | |
3D7/FC27 | 4 (66.7) | 37 (78.7) | 55 (62.5) | 25 (62.5) | 121 (66.9) | |
Total | 6 (100) | 45 (95.7) | 82 (93.2) | 40 (100) | 173 (95.6) | |
MOI | 1.83 | 2.31 | 2.01 | 2.1 | 2.01 | |
Multiclonal isolates | 6 (100) | 47 (100) | 87 (98.9) | 41 (100) | 181 (100) | |
Overall MOI | 5.17 | 6.02 | 5.53 | 5.13 | 5.51 | |