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Table 2 Genetic diversity of Plasmodium falciparum msp1 and msp2 among parasitaemic groups of symptomatic patients on Bioko Island, Equatorial Guinea (2011–2014)

From: Genetic diversity and allele frequencies of Plasmodium falciparum msp1 and msp2 in parasite isolates from Bioko Island, Equatorial Guinea

Gene Allelic type Parasite density (no. of parasites/μl)
< 1000 1000–9999 ≥ 10,000 (%)
n (%) n (%) n (%)
(n = 14) (n = 74) (n = 93)
msp1 MAD20 1 (7.1) 0 1 (1.1)
K1/MAD20 3 (21.4) 22 (29.7) 25 (27.8)
K1/RO33 1 (7.1) 1 (1.4) 1 (1.1)
MAD20/RO33 0 4 (5.4) 1 (1.1)
K1/MAD20/RO33 9 (64.3) 46 (62.2) 63 (70)
Total 13 (92.9) 73 (98.6) 90 (49.72)
MOI 3.07 3.63 3.48
msp2 3D7 3 (21.4) 25 (33.8) 20 (21.5)
FC27 1 (7.1) 2 (2.7) 1 (1.1)
3D7/FC27 7 (50) 45 (60.8) 69 (74.2)
Total 7 (50) 45 (60.8) 69 (74.2)
MOI 1.73 1.90 2.31
Multiclonal isolates 14 (100) 74 (100) 93 (100)
Overall MOI 4.43 5.51 5.77
  1. n number of individuals, MOI multiplicity of infection