Fig. 2

Graphical reports of compounds 4a and 4c. a Compound values (blue line) superimposed on an oral library with min and max ranges (pink and red) during a compound complexity analysis. b Golden Triangle Rule evaluation: compounds located in the yellow triangle are likely to have an optimal permeability and a good metabolic stability. c For an oral absorption evaluation, compound values (blue line) should fall within RO5 and Veber rules area (light green line). d The Oral Property Space, obtained by applying a Principal Component Analysis of the 15 principal physicochemical descriptors of user’s compound (red), compared to two oral sub-libraries extracted from eDrugs (blue) and DrugBank (orange)