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Table 4 Correlation between area under the curve parasitaemia during study days 90–240 and IgG subclass titers

From: Immunoglobulin G subclass and antibody avidity responses in Malian children immunized with Plasmodium falciparum apical membrane antigen 1 vaccine candidate FMP2.1/AS02A

 

FMP2.1/AS02A vaccine group (n = 66)

Control group (n = 22)

R

P-value

R

P-value

IgG1 day 90

0.077

0.54

0.22

0.32

IgG2 day 90

0.026

0.84

0.11

0.64

IgG3 day 90

0.29

0.019

0.14

0.53

IgG4 day 90

− 0.057

0.66

0.22

0.33

IgG1 day 240

0.24

0.052

0.041

0.86

IgG2 day 240

0.13

0.28

0.11

0.62

IgG3 day 240

0.32

0.010

0.23

0.30

IgG4 day 240

− 0.16

0.20

0.24

0.28

  1. Italic values denote significant results. Volunteers who were treated for a clinical malaria episode before day 90 were excluded from this analysis. R, Spearman correlation coefficient
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Malaria Journal

ISSN: 1475-2875

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