Fig. 3

Efficacy of compounds in the Pathogen Box on P. falciparum 3D7. The scatter-plot of growth inhibition rates of parasites treated with 5 µM of each of the 400 compounds from the Pathogen Box. The horizontal and vertical axes indicate the growth inhibition rate of parasites treated with the compounds for 24 and 48 h, respectively. Growth inhibition of 70% was defined as a cut-off point for compound efficacy. Colour indications are as follows: red, > 70% (24 h) and > 70% (48 h); blue, < 70% (24 h) and < 70% (48 h); orange, < 70% (24 h) and > 70% (48 h); and green, > 70% (24 h) and < 70% (48 h)