Skip to main content

Table 1 List of 141 compounds exhibiting anti-malarial activity against P. falciparum 3D7

From: Application of the automated haematology analyzer XN-30 for discovery and development of anti-malarial drugs

Growth inhibition (%)
Plate # Position Compound ID 24 h 48 h Type Disease set
A #1 A02 MMV010764 66.1 97.3 IV MAL
A #2 B03 MMV000907 97.6 108.7 III MAL
A #3 C02 MMV084603 98.6 103.6 III MAL
A #4 C04 MMV688888 100.1 100.1 III TUB
A #5 D04 MMV661713 100.1 107.2 II TUB
A #6 E03 MMV676350 99.8 107.6 II MAL
A #7 F02 MMV026020 91.5 117.6 III MAL
A #8 H08 MMV676474 86.7 38.1 III TUB
B #1 A03 MMV652003 97.3 93.2 I KIN
B #2 A04 MMV000062 100.1 99.0 I REF
B #3 A05 MMV006372 100.1 100.1 III MAL
B #4 A09 MMV020623b 99.9 96.8 I MAL
B #5 A10 MMV020512 95.7 97.7 I MAL
B #6 B03 MMV676604 57.0 96.1 IV KIN
B #7 B07 MMV020982 100.1 97.9 II MAL
B #8 B08 MMV020120 100.1 97.9 I MAL
B #9 B10 MMV007638 89.5 98.4 III MAL
B #10 B11 MMV021057 100.1 97.2 I MAL
B #11 C07 MMV020136b 100.1 98.1 I MAL
B #12 C08 MMV020710b 99.9 97.9 I MAL
B #13 C09 MMV020517 82.4 90.5 III MAL
B #14 C10 MMV019721 100.1 98.1 I MAL
B #15 D02 MMV020537 99.9 100.6 I MAL
B #16 D05 MMV000063 89.8 83.0 III REF
B #17 D08 MMV020520b 100.1 98.4 I MAL
B #18 D09 MMV019234 100.1 95.6 II MAL
B #19 D10 MMV016136 99.9 96.9 I MAL
B #20 E07 MMV676442 100.1 98.8 I MAL
B #21 E09 MMV024397 100.1 100.6 I MAL
B #22 E10 MMV019807 99.9 98.5 I MAL
B #23 F02 MMV019189 5.4 91.4 IV MAL
B #24 F05 MMV637229 98.8 97.6 I TRI
B #25 F07 MMV020321 78.5 62.4 III MAL
B #26 F08 MMV019087 95.5 88.3 III MAL
B #27 F09 MMV676528 99.6 98.1 I MAL
B #28 F10 MMV020320 40.6 84.5 IV MAL
B #29 F11 MMV085210b 100.1 96.6 I MAL
B #30 G05 MMV689480 74.8 48.7 III REF
B #31 G07 MMV006239b 100.1 98.7 I MAL
B #32 G08 MMV000858b 99.9 96.9 I MAL
B #33 G09 MMV006741 100.1 103.7 II MAL
B #34 H02 MMV676602 77.3 97.3 III KIN
B #35 H03 MMV000016c 99.9 100.4 I REF
B #36 H05 MMV668727 15.7 97.6 IV ONC
B #37 H08 MMV006901 100.1 119.0 II MAL
B #38 H09 MMV020391b 99.9 97.2 I MAL
C #1 A05 MMV688122 90.8 77.9 III TUB
C #2 B02 MMV020388 100.4 96.7 II MAL
C #3 B03 MMV688547 90.8 85.8 III KIN
C #4 B05 MMV687749 99.6 96.7 II TUB
C #5 C03 MMV688283 81.6 105.5 II KIN
C #6 C09 MMV688361 97.5 86.3 III KIN
C #7 C11 MMV022236 89.1 93.8 III MAL
C #8 D05 MMV687248 100.0 100.8 II TUB
C #9 D11 MMV1030799 99.6 99.0 III MAL
C #10 E10 MMV021375 96.6 93.0 II MAL
C #11 F03 MMV688179 27.1 74.3 IV KIN
C #12 F04 MMV023969 100.4 98.5 II TUB
C #13 F08 MMV687807 71.9 97.8 III TUB
C #14 G03 MMV675993 100.0 98.0 I CRY
C #15 G04 MMV021660 100.4 101.9 II TUB
C #16 G06 MMV687273 97.1 52.0 III TUB
C #17 G11 MMV688703 97.5 95.6 II TOX
C #18 H07 MMV024311 100.0 97.6 I TUB
D #1 A02 MMV026468 74.4 95.7 III MAL
D #2 A03 MMV020670 93.7 99.1 III MAL
D #3 A04 MMV023953 30.6 97.8 II MAL
D #4 A05 MMV010576 99.7 99.9 I MAL
D #5 A06 MMV032967 97.7 98.3 II MAL
D #6 A07 MMV031011 89.7 102.2 II MAL
D #7 A09 MMV688362 99.7 98.5 III KIN
D #8 A11 MMV026356 100.3 98.4 III MAL
D #9 B02 MMV011511 95.4 98.2 II MAL
D #10 B04 MMV007471 99.5 93.8 I MAL
D #11 B05 MMV024829 99.7 105.4 II MAL
D #12 B07 MMV022029 95.1 107.2 II MAL
D #13 B09 MMV688180 27.2 96.1 IV KIN
D #14 B10 MMV024035 77.3 97.3 II MAL
D #15 C03 MMV006833 93.4 97.8 III MAL
D #16 C04 MMV026490 74.4 97.6 III MAL
D #17 C05 MMV687246 85.3 115.2 II MAL
D #18 C07 MMV024114 79.9 98.7 II MAL
D #19 D03 MMV020081b 100.0 99.3 I MAL
D #20 D04 MMV026550 6.4 92.5 IV MAL
D #21 D07 MMV023860 85.1 96.5 III MAL
D #22 D09 MMV023949 93.1 95.7 II MAL
D #23 D11 MMV024406 87.4 113.1 II MAL
D #24 E02 MMV023233 100.9 102.6 II MAL
D #25 E03 MMV085230 86.5 80.2 III MAL
D #26 E04 MMV085071a 99.2 98.8 III MAL
D #27 E05 MMV659004 32.0 89.9 IV KIN
D #28 E06 MMV676260 90.5 97.6 II MAL
D #29 E08 MMV032995 75.5 90.3 III MAL
D #30 E09 MMV688279 100.0 95.6 I KIN
D #31 E10 MMV688271 100.3 97.6 III KIN
D #32 F03 MMV011765 3.5 94.9 IV MAL
D #33 F04 MMV024937 92.0 96.2 II MAL
D #34 F05 MMV085499 99.2 98.9 I MAL
D #35 F06 MMV023985 70.1 101.9 IV MAL
D #36 F07 MMV024195 45.0 109.3 II MAL
D #37 F11 MMV687812 96.3 106.0 II TUB
D #38 G02 MMV007803 100.0 94.9 III MAL
D #39 G03 MMV001059b 100.3 100.2 I MAL
D #40 G04 MMV011691 94.9 96.9 III MAL
D #41 G05 MMV676877 99.2 100.5 III MAL
D #42 G06 MMV663250 99.7 101.0 III MAL
D #43 G11 MMV676411 88.5 96.5 III TUB
D #44 H02 MMV007133 11.3 96.2 IV MAL
D #45 H03 MMV022478 100.9 98.6 II MAL
D #46 H05 MMV676881 0.9 90.0 IV MAL
D #47 H06 MMV024443 47.0 96.8 IV MAL
D #48 H08 MMV023388 95.1 97.6 II MAL
D #49 H09 MMV675968 96.3 100.2 II CRY
D #50 H11 MMV688980b 100.0 97.2 I MAL
E #1 A02 MMV011229 101.0 99.0 I MAL
E #2 A06 MMV688775 90.6 90.5 III REF
E #3 A08 MMV393144 98.3 93.5 III MAL
E #4 A11 MMV019993 99.3 99.6 I MAL
E #5 B02 MMV687794 9.8 81.6 IV MAL
E #6 B08 MMV023183 99.2 109.1 II MAL
E #7 C04 MMV671636 100.0 99.2 I ONC
E #8 C08 MMV687765 99.7 99.7 II TUB
E #9 C09 MMV020165 91.4 84.0 III MAL
E #10 D02 MMV688766 74.8 98.7 III SCH
E #11 D04 MMV667494 100.4 99.6 I MAL
E #12 D05 MMV028694 42.9 96.3 IV MAL
E #13 D07 MMV688345 57.6 92.9 IV TOX
E #14 D08 MMV010545 98.1 101.2 III MAL
E #15 E02 MMV020289 100.1 99.0 III MAL
E #16 E04 MMV634140 100.4 97.1 I MAL
E #17 E05 MMV030734 12.6 95.8 IV MAL
E #18 E09 MMV407834 18.4 90.5 IV MAL
E #19 F02 MMV019551 99.1 96.3 I MAL
E #20 F09 MMV026313 46.2 89.4 IV MAL
E #21 G04 MMV021013 99.3 100.0 III TUB
E #22 G05 MMV392832 101.5 103.4 II MAL
E #23 G06 MMV688754 100.2 98.9 III KIN
E #24 G08 MMV658988 60.8 95.7 IV KIN
E #25 G09 MMV084864 101.5 97.5 II MAL
E #26 H05 MMV688978 100.0 102.4 I REF
E #27 H10 MMV688550 95.1 96.4 III KIN
  1. MAL malaria, TUB tuberculosis, KIN kinetoplastids, REF reference compounds, TRI trichuriasis, ONC onchocerciasis, CRY cryptosporidiosis, TOX toxoplasmosis, SCH schistosomiasis
  2. aPositive compounds described in Tong et al. [19]
  3. bPositive compounds described in Dennis et al. [20]
  4. cMefloquine