Skip to main content

Table 1 List of 141 compounds exhibiting anti-malarial activity against P. falciparum 3D7

From: Application of the automated haematology analyzer XN-30 for discovery and development of anti-malarial drugs

Growth inhibition (%)

Plate

#

Position

Compound ID

24 h

48 h

Type

Disease set

A

#1

A02

MMV010764

66.1

97.3

IV

MAL

A

#2

B03

MMV000907

97.6

108.7

III

MAL

A

#3

C02

MMV084603

98.6

103.6

III

MAL

A

#4

C04

MMV688888

100.1

100.1

III

TUB

A

#5

D04

MMV661713

100.1

107.2

II

TUB

A

#6

E03

MMV676350

99.8

107.6

II

MAL

A

#7

F02

MMV026020

91.5

117.6

III

MAL

A

#8

H08

MMV676474

86.7

38.1

III

TUB

B

#1

A03

MMV652003

97.3

93.2

I

KIN

B

#2

A04

MMV000062

100.1

99.0

I

REF

B

#3

A05

MMV006372

100.1

100.1

III

MAL

B

#4

A09

MMV020623b

99.9

96.8

I

MAL

B

#5

A10

MMV020512

95.7

97.7

I

MAL

B

#6

B03

MMV676604

57.0

96.1

IV

KIN

B

#7

B07

MMV020982

100.1

97.9

II

MAL

B

#8

B08

MMV020120

100.1

97.9

I

MAL

B

#9

B10

MMV007638

89.5

98.4

III

MAL

B

#10

B11

MMV021057

100.1

97.2

I

MAL

B

#11

C07

MMV020136b

100.1

98.1

I

MAL

B

#12

C08

MMV020710b

99.9

97.9

I

MAL

B

#13

C09

MMV020517

82.4

90.5

III

MAL

B

#14

C10

MMV019721

100.1

98.1

I

MAL

B

#15

D02

MMV020537

99.9

100.6

I

MAL

B

#16

D05

MMV000063

89.8

83.0

III

REF

B

#17

D08

MMV020520b

100.1

98.4

I

MAL

B

#18

D09

MMV019234

100.1

95.6

II

MAL

B

#19

D10

MMV016136

99.9

96.9

I

MAL

B

#20

E07

MMV676442

100.1

98.8

I

MAL

B

#21

E09

MMV024397

100.1

100.6

I

MAL

B

#22

E10

MMV019807

99.9

98.5

I

MAL

B

#23

F02

MMV019189

5.4

91.4

IV

MAL

B

#24

F05

MMV637229

98.8

97.6

I

TRI

B

#25

F07

MMV020321

78.5

62.4

III

MAL

B

#26

F08

MMV019087

95.5

88.3

III

MAL

B

#27

F09

MMV676528

99.6

98.1

I

MAL

B

#28

F10

MMV020320

40.6

84.5

IV

MAL

B

#29

F11

MMV085210b

100.1

96.6

I

MAL

B

#30

G05

MMV689480

74.8

48.7

III

REF

B

#31

G07

MMV006239b

100.1

98.7

I

MAL

B

#32

G08

MMV000858b

99.9

96.9

I

MAL

B

#33

G09

MMV006741

100.1

103.7

II

MAL

B

#34

H02

MMV676602

77.3

97.3

III

KIN

B

#35

H03

MMV000016c

99.9

100.4

I

REF

B

#36

H05

MMV668727

15.7

97.6

IV

ONC

B

#37

H08

MMV006901

100.1

119.0

II

MAL

B

#38

H09

MMV020391b

99.9

97.2

I

MAL

C

#1

A05

MMV688122

90.8

77.9

III

TUB

C

#2

B02

MMV020388

100.4

96.7

II

MAL

C

#3

B03

MMV688547

90.8

85.8

III

KIN

C

#4

B05

MMV687749

99.6

96.7

II

TUB

C

#5

C03

MMV688283

81.6

105.5

II

KIN

C

#6

C09

MMV688361

97.5

86.3

III

KIN

C

#7

C11

MMV022236

89.1

93.8

III

MAL

C

#8

D05

MMV687248

100.0

100.8

II

TUB

C

#9

D11

MMV1030799

99.6

99.0

III

MAL

C

#10

E10

MMV021375

96.6

93.0

II

MAL

C

#11

F03

MMV688179

27.1

74.3

IV

KIN

C

#12

F04

MMV023969

100.4

98.5

II

TUB

C

#13

F08

MMV687807

71.9

97.8

III

TUB

C

#14

G03

MMV675993

100.0

98.0

I

CRY

C

#15

G04

MMV021660

100.4

101.9

II

TUB

C

#16

G06

MMV687273

97.1

52.0

III

TUB

C

#17

G11

MMV688703

97.5

95.6

II

TOX

C

#18

H07

MMV024311

100.0

97.6

I

TUB

D

#1

A02

MMV026468

74.4

95.7

III

MAL

D

#2

A03

MMV020670

93.7

99.1

III

MAL

D

#3

A04

MMV023953

30.6

97.8

II

MAL

D

#4

A05

MMV010576

99.7

99.9

I

MAL

D

#5

A06

MMV032967

97.7

98.3

II

MAL

D

#6

A07

MMV031011

89.7

102.2

II

MAL

D

#7

A09

MMV688362

99.7

98.5

III

KIN

D

#8

A11

MMV026356

100.3

98.4

III

MAL

D

#9

B02

MMV011511

95.4

98.2

II

MAL

D

#10

B04

MMV007471

99.5

93.8

I

MAL

D

#11

B05

MMV024829

99.7

105.4

II

MAL

D

#12

B07

MMV022029

95.1

107.2

II

MAL

D

#13

B09

MMV688180

27.2

96.1

IV

KIN

D

#14

B10

MMV024035

77.3

97.3

II

MAL

D

#15

C03

MMV006833

93.4

97.8

III

MAL

D

#16

C04

MMV026490

74.4

97.6

III

MAL

D

#17

C05

MMV687246

85.3

115.2

II

MAL

D

#18

C07

MMV024114

79.9

98.7

II

MAL

D

#19

D03

MMV020081b

100.0

99.3

I

MAL

D

#20

D04

MMV026550

6.4

92.5

IV

MAL

D

#21

D07

MMV023860

85.1

96.5

III

MAL

D

#22

D09

MMV023949

93.1

95.7

II

MAL

D

#23

D11

MMV024406

87.4

113.1

II

MAL

D

#24

E02

MMV023233

100.9

102.6

II

MAL

D

#25

E03

MMV085230

86.5

80.2

III

MAL

D

#26

E04

MMV085071a

99.2

98.8

III

MAL

D

#27

E05

MMV659004

32.0

89.9

IV

KIN

D

#28

E06

MMV676260

90.5

97.6

II

MAL

D

#29

E08

MMV032995

75.5

90.3

III

MAL

D

#30

E09

MMV688279

100.0

95.6

I

KIN

D

#31

E10

MMV688271

100.3

97.6

III

KIN

D

#32

F03

MMV011765

3.5

94.9

IV

MAL

D

#33

F04

MMV024937

92.0

96.2

II

MAL

D

#34

F05

MMV085499

99.2

98.9

I

MAL

D

#35

F06

MMV023985

70.1

101.9

IV

MAL

D

#36

F07

MMV024195

45.0

109.3

II

MAL

D

#37

F11

MMV687812

96.3

106.0

II

TUB

D

#38

G02

MMV007803

100.0

94.9

III

MAL

D

#39

G03

MMV001059b

100.3

100.2

I

MAL

D

#40

G04

MMV011691

94.9

96.9

III

MAL

D

#41

G05

MMV676877

99.2

100.5

III

MAL

D

#42

G06

MMV663250

99.7

101.0

III

MAL

D

#43

G11

MMV676411

88.5

96.5

III

TUB

D

#44

H02

MMV007133

11.3

96.2

IV

MAL

D

#45

H03

MMV022478

100.9

98.6

II

MAL

D

#46

H05

MMV676881

0.9

90.0

IV

MAL

D

#47

H06

MMV024443

47.0

96.8

IV

MAL

D

#48

H08

MMV023388

95.1

97.6

II

MAL

D

#49

H09

MMV675968

96.3

100.2

II

CRY

D

#50

H11

MMV688980b

100.0

97.2

I

MAL

E

#1

A02

MMV011229

101.0

99.0

I

MAL

E

#2

A06

MMV688775

90.6

90.5

III

REF

E

#3

A08

MMV393144

98.3

93.5

III

MAL

E

#4

A11

MMV019993

99.3

99.6

I

MAL

E

#5

B02

MMV687794

9.8

81.6

IV

MAL

E

#6

B08

MMV023183

99.2

109.1

II

MAL

E

#7

C04

MMV671636

100.0

99.2

I

ONC

E

#8

C08

MMV687765

99.7

99.7

II

TUB

E

#9

C09

MMV020165

91.4

84.0

III

MAL

E

#10

D02

MMV688766

74.8

98.7

III

SCH

E

#11

D04

MMV667494

100.4

99.6

I

MAL

E

#12

D05

MMV028694

42.9

96.3

IV

MAL

E

#13

D07

MMV688345

57.6

92.9

IV

TOX

E

#14

D08

MMV010545

98.1

101.2

III

MAL

E

#15

E02

MMV020289

100.1

99.0

III

MAL

E

#16

E04

MMV634140

100.4

97.1

I

MAL

E

#17

E05

MMV030734

12.6

95.8

IV

MAL

E

#18

E09

MMV407834

18.4

90.5

IV

MAL

E

#19

F02

MMV019551

99.1

96.3

I

MAL

E

#20

F09

MMV026313

46.2

89.4

IV

MAL

E

#21

G04

MMV021013

99.3

100.0

III

TUB

E

#22

G05

MMV392832

101.5

103.4

II

MAL

E

#23

G06

MMV688754

100.2

98.9

III

KIN

E

#24

G08

MMV658988

60.8

95.7

IV

KIN

E

#25

G09

MMV084864

101.5

97.5

II

MAL

E

#26

H05

MMV688978

100.0

102.4

I

REF

E

#27

H10

MMV688550

95.1

96.4

III

KIN

  1. MAL malaria, TUB tuberculosis, KIN kinetoplastids, REF reference compounds, TRI trichuriasis, ONC onchocerciasis, CRY cryptosporidiosis, TOX toxoplasmosis, SCH schistosomiasis
  2. aPositive compounds described in Tong et al. [19]
  3. bPositive compounds described in Dennis et al. [20]
  4. cMefloquine
Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us