|
Antigen tested/parasite isolate
|
No episodea (n = 457)
|
≥ 1 episode before 6 months of agea (n = 31)
|
p valueb
|
≥ 1 episode between 6 and 18 months of agea (n = 113)
|
p valueb
|
|---|
|
MSP1 19 kDc
|
2.36 (0.51, 5.73)
|
6.16 (1.92, 11.16)
|
0.0071
|
4.71 (1.43, 21.25)
|
< 0.0001
|
|
224 (49.0)
|
24 (77.5)
|
0.002
|
79 (69.9)
|
< 0.0001
|
|
MSP2d
|
2.76 (0.79, 8.23)
|
5.76 (1.01, 10.55)
|
0.1043
|
3.06 (1.06, 13.97)
|
0.3165
|
|
113 (24.7)
|
12 (38.8)
|
0.084
|
37 (32.7)
|
0.083
|
|
EBA175e
|
3.49 (1.96, 17.05)
|
3.25 (1.89, 8.79)
|
0.5785
|
3.19 (1.93, 9.91)
|
0.3753
|
|
50 (10.9)
|
3 (9.7)
|
0.827
|
16 (14.2)
|
0.338
|
|
Rh2A9f
|
7.03 (3.97, 13.13)
|
8.24 (4.41, 17.32)
|
0.3790
|
7.92 (4.12, 15.87)
|
0.2223
|
|
108 (23.6)
|
10 (32.3)
|
0.278
|
33 (29.2)
|
0.219
|
|
Schizont
|
2.95 (1.02, 7.24)
|
7.40 (2.24, 13.97)
|
0.0211
|
4.70 (1.77, 14.87)
|
0.0018
|
|
222 (48.6)
|
23 (74.2)
|
0.006
|
80 (70.8)
|
< 0.0001
|
|
E8Bg
|
0 (0, 0.15)
|
0.03 (0, 1.11)
|
0.0177
|
0 (0, 0.26)
|
0.0967
|
|
24 (5.3)
|
10 (32.3)
|
< 0.0001
|
9 (7.9)
|
0.269
|
|
R29g
|
0 (0, 0.002)
|
0 (0, 0.43)
|
0.0424
|
0 (0, 0.24)
|
0.2341
|
|
13 (2.8)
|
5 (16.2)
|
< 0.0001
|
3 (2.6)
|
0.913
|
|
3D7g
|
0 (0, 0.33)
|
0.01 (0, 0.37)
|
0.4718
|
0 (0, 0.42)
|
0.8673
|
|
36 (7.9)
|
4 (12.9)
|
0.324
|
10 (8.9)
|
0.734
|
- Significant p value in italic format
- aFor each antigen represented, row 1: median antibody level (interquartile range); row 2: number of seropositive children (%)
- bp value calculated by Mann–Whitney test or Chi squared test for antibody level or seropositivity, respectively
- cMerozoite surface protein 1
- dMerozoite surface protein 2
- eErythrocyte binding antigen 175
- fReticulocyte binding protein homologue 2A
- gVariant surface antigen antibody responses
