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Fig. 4 | Malaria Journal

Fig. 4

From: Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studies

Fig. 4

Inhibition of PvG6PD with ellagic acid. The Lineweaver–Burk plots for titrating G6P (a) or NADP+ (b) show that the higher the concentration of ellagic acid, the lower the Vmax, while the KM values increased. This indicates that ellagic acid acts as a mixed-type inhibitor of PvG6PD with respect to both G6P and NADP+. Representative graphs from at least four independent determinations are shown

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Malaria Journal

ISSN: 1475-2875

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