Fig. 9From: Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studiesInhibition type of 4 (vz1732) towards PfGluPho. The compound shows non-competitive inhibition against both G6P (a) and NADP+ (b). The higher the concentration of 4 (vz1732), the lower the Vmax, while the KM values for G6P and NADP+ stayed constant. Representative graphs from two independent determinations are shownBack to article page