Skip to main content

Table 2 Rates of clinical malaria from a passively followed cohort of children under 5 years of age

From: Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: evidence from health facility data from Benin

  Malaria incidence per person-year (95% CI) [cases/person-years] Rate ratio (95% CI) Rate ratio excluding outliersa (95% CI)
January–July 2013
Overall incidence 0.12 (0.06–0.22) [124/1057]
Lower resistance (mortality equal to or above median value of 95.3%) 0.05 (0.02–0.13) [28/530] 1 1
Higher resistance (mortality below median value of 95.3%) 0.18 (0.09–0.39) [96/527] 3.45 (1.17–10.20)
p = 0.027
2.48 (0.88–7.00)
p = 0.082
Effect per 10% reduction in bioassay mortality 1.46 (0.84–2.54)
p = 0.170
1.11 (0.68–1.82)
p = 0.667
August–December 2013
Overall incidence 0.31 (0.19–0.49) [240/778]
Lower resistance (mortality equal to or above median value of 93.9%) 0.42 (0.22–0.80) [158/373] 1 1
Higher resistance (mortality below median value of 93.9%) 0.20 (0.11–0.39) [82/405] 0.48 (0.21–1.11)
p = 0.083
0.60 (0.26–1.37)
p = 0.214
Effect per 10% reduction in bioassay mortality 0.45 (0.16–1.33)
p = 0.143
0.46 (0.14–1.58)
p = 0.208
January–December 2014
Overall incidence 0.23 (0.13–0.41) [420/1804]
Lower resistance (mortality equal to or above median value of 47.2%) 0.09 (0.04–0.25) [86/907] 1 1
Higher resistance (mortality below median value of 47.2%) 0.37 (0.20–0.70) [334/897] 3.93 (1.34–11.51) p = 0.015 2.46 (0.89–6.78)
p = 0.080
Effect per 10% reduction in bioassay mortality 1.61 (1.21–2.13) p = 0.002 1.28 (0.91–1.79)
p = 0.144
January 2013–December 2014 (all time periods combined)
Overall incidence 0.22 (0.14–0.34) [784/3639]
Lower resistance (mortality equal to or above median value of 47.2%) 0.20 (0.13–0.31) [270/1378] 1 1
Higher resistance (mortality below median value of 91.3%) 0.23 (0.13–0.40) [514/2261] 1.11 (0.52–2.35)
p = 0.777
0.89 (0.42–1.86)
p = 0.738
Effect per 10% reduction in bioassay mortality 1.50 (1.14–1.97)
p = 0.005
1.17 (0.90–1.53)
p = 0.239
  1. a Defined as cluster level rate greater than 2 standard deviations above the mean cluster-level rate