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Fig. 1 | Malaria Journal

Fig. 1

From: Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

Fig. 1

Determination of IVIS machine exposure time for determining full body bioluminescence measurements in ICR-CD1 mice infected with 1 × 105 luciferase-expressing Plasmodium berghei infected erythrocytes. Ten ICR-CD1 female mice were infected IP with 1 × 105 luciferase-expressing P. berghei infected erythrocytes. Data shown represents full body luminescence measured for all 10 mice on day 3–5 post infections and 7 mice on day 6 post infections. Three ICR-CD1 mice had to be removed from the study on day 6 post infections before the whole-body bioluminescence readings were taken because they became sick with malaria. The asterisk sign asterisk indicates presence of saturated images in one or more study mice. One and 5 min exposure, as well as auto exposure settings were used to measure whole-body bioluminescence signal

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