Table 1 General characteristics at enrolment as a function of weight status
From: Relationship between weight status and anti-malarial drug efficacy and safety in children in Mali
| Â | Underweight n (%) | Normal weight n (%) | Overweight n (%) | p-value |
|---|---|---|---|---|
AS + AQ arm (n = 250) | 19 (7.6) | 137 (54.8) | 94 (37.6) | 0.11 |
AS + SP arm (n = 248) | 29 (11.69) | 138 (55.65) | 81 (32.66) | |
AS arm (n = 251) | 30 (11.95) | 152 (60.56) | 69 (27.49) | |
Male (n = 354) | 36 (10.17) | 201 (56.78) | 117 (33.05) | 0.95 |
Female (n = 395) | 42 (10.63) | 226 (57.22) | 127 (32.15) | |
< 5 (n = 513) | 49 (9.55) | 259 (50.49) | 205 (39.96) | < 0.0001 |
≥ 5 (n = 236) | 29 (12.29) | 168 (71.19) | 39 (16.53) | |
Temperature (°C) median (interquartile range) | 38.50 (37.80, 39.18) | 38.40 (37.80, 38.90) | 38.65 (38.00, 39.10) |  |
P. falciparum (/µl) median (interquartile range) | 17,800 (5925, 33,060) | 14,850 (7162, 28,160) | 17,660 (9638, 36,380) | |
Haemoglobin (g/dl) median (interquartile range) | 9.85 (8.48, 11.40) | 10.59 (9.50, 11.80) | 9.50 (8.48, 10.90) | |
ASAT (UI/l) median (interquartile range) | 32.20 (23.30, 46.70) | 36.00 (27.70, 43.90) | 38.20 (29.40, 48.30) | |
ALAT (UI/l) median (interquartile range) | 15.15 (11.08, 20.10) | 17.00 (12.50, 23.87) | 23.31 (12.00, 24.00) | |
Creatinine (mg/dl) median (interquartile range) | 0.52 (0.46, 0.75) | 0.55 (0.48, 0.68) | 0.53 (0.44, 0.66) | |
Artesunate (mean ± SD in mg/kg) | 58.22 ± 32.29 | 69.40 ± 29.39 | 61.57 ± 22.77 | |
Amodiaquine (mean ± SD in mg/kg) | 165.08 ± 69.89 | 185.3 ± 89.99 | 155.82 ± 48.07 | |
Sulfadoxine (mean ± SD in mg/kg) | 354.17 ± 185.93 | 444.85 ± 194.70 | 387.66 ± 199.75 |