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Table 2 Treatment outcome without PCR correction

From: Relationship between weight status and anti-malarial drug efficacy and safety in children in Mali

 

Underweight

(n = 22)

Normal weight

(n = 137)

Overweight

(n = 92)

p-value

n (%)

n (%)

n (%)

AS + AQ

 ACPR

18 (94.74)

125 (91.24)

74 (80.43)

0.03

 ETF

0 (0)

0 (0)

1 (1.09)

–

 LCF

3 (3.9)

4 (2.92)

8 (8.7)

0.08

 LPF

1 (5.26)

8 (5.84)

9 (9.78)

0.49

AS + SP

 ACPR

28 (96.55)

133 (91.24)

75 (97.4)

0.92

 ETF

0 (0)

0 (0)

0 (0)

–

 LCF

0 (0)

2 (1.47)

1 (1.3)

0.81

 LPF

1 (3.45)

1 (0.74)

1 (1.3)

0.49

AS

 ACPR

25 (83.33)

105 (69.54)

43 (63.24)

0.14

 ETF

0 (0)

0 (0)

0 (0)

–

 LCF

3 (10)

15 (9.93)

11 (16.17)

0.39

 LPF

2 (6.67)

31 (20.53)

14 (20.59)

0.19

  1. ACPR: adequate clinical and parasitological response; ETF: early treatment failure; LCF: late clinical failure, LPF: late parasitological failure