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Table 2 The distribution of diagnostic discriminatory accuracy, likelihood ratios and the predictive values of RDT against microscopy test by selected children characteristics in the Nigeria 2015 MIS

From: On the discriminatory and predictive accuracy of the RDT against the microscopy in the diagnosis of malaria among under-five children in Nigeria

Characteristics

Sensitivity

Specificity

Total agreement

LR+

LR−

PPV

NPV

% (95% CI)

% (95% CI)

% (95% CI)

LR+ (95% CI)

LR− (95% CI)

% (95% CI)

% (95% CI)

Total

87.6 (85.9–89.2)

75.8 (74.4–77.1)

79.0 (77.9–80.0)

3.6 (3.4–3.8)

0.16 (0.14–0.19)

57.5 (56.1–58.9)

94.2 (93.5–94.9)

Children age

 0–6 Months

85.7 (42.099.3)

90.1 (50.195.6)

89.7 (83.096.5)

8.7 (4.018.7)

0.16 (0.03–0.97)

46.1 (20.473.8)

98.5 (90.599.9)

 7–23 Months

86.1 (81.989.3)

80.7 (78.682.7)

81.8 (80.083.6)

4.5 (4.05.0)

0.17 (0.13–0.22)

53.3 (59.157.4)

95.8 (94.496.8)

 24–59 Months

88.1 (86.089.8)

72.9 (71.174.5)

77.5 (76.278.8)

3.2 (3.03.5)

0.16 (0.14–0.19)

58.9 (56.661.2)

93.2 (92.094.2)

Sex

 Male

87.6 (85.1–89.8)

74.7 (72.876.6)

78.3 (76.7–79.8)

3.5 (3.2–3.7)

0.17 (0.14–0.20)

57.2 (55.3–59.1)

93.9 (92.8–94.9)

 Female

87.6 (85.0–89.9)

76.9 (75.078.7)

79.7 (78.2–81.2)

3.8 (3.5–4.1)

0.16 (0.13–0.20)

57.8 (55.7–59.8)

94.5 (93.4–95.4)

Location

 Urban

83.6 (78.388.1)

86.3 (84.687.9)

86.0 (96.798.1)

6.1 (5.47.0)

0.19 (0.14–0.25)

45.5 (42.348.8)

97.5 (96.798.1)

 Rural

88.3 (86.590.0)

68.3 (66.470.1)

75.3 (72.976.7)

2.8 (2.63.0)

0.17 (0.15–0.20)

60.2 (58.761.7)

91.5 (90.292.6)

Zone

 North Central

92.8 (89.595.3)

73.5 (70.476.5)

79.1 (76.681.4)

3.5 (3.13.9)

0.10 (0.070.14)

58.5 (55.761.3)

96.2 (94.597.4)

 North East

86.7 (82.390.4)

74.3 (71.277.3)

77.6 (75.080.0)

3.4 (3.03.8)

0.18 (0.130.24)

54.5 (51.457.7)

94.0 (92.195.5)

 North West

85.0 (81.987.8)

63.3 (59.966.6)

72.2 (69.874.5)

2.3 (2.12.6)

0.24 (0.190.29)

61.5 (59.363.7)

86.0 (83.488.2)

 South East

94.0 (86.598.0)

80.6 (76.884.4)

82.6 (79.285.6)

4.9 (4.05.9)

0.07 (0.030.17)

45.4 (40.750.1)

98.7 (97.199.5)

 South South

79.5 (72.185.6)

85.4 (82.388.1)

84.2 (81.486.8)

5.5 (4.46.7)

0.24 (0.180.33)

58.3 (53.063.3)

94.2 (92.295.7)

 South West

93.4 (87.597.1)

84.9 (81.887.7)

86.3 (83.688.7)

6.2 (5.17.5)

0.08 (0.040.15)

55.3 (50.560.1)

98.5 (97.199.2)

Fever in the last 2 weeks

 No

86.5 (83.8–88.9)

82.7 (81.284.2)

83.6 (82.384.9)

5.0 (4.65.5)

0.16 (0.140.20)

60.1 (57.962.3)

95.3 (94.4–96.1)

 Yes

88.6 (86.2–90.7)

65.8 (63.568.1)

73.2 (71.474.9)

2.6 (2.42.8)

0.17 (0.140.21)

55.4 (53.657.1)

92.4 (90.9–93.6)

Treated fever

 No

92.8 (87.796.4)

70.5 (63.177.2)

81.1 (76.485.2)

3.2 (2.54.0)

0.10 (0.060.18)

73.9 (69.178.1)

91.7 (86.2–95.2)

 Yes

87.6 (84.490.0)

65.3 (62.967.7)

92.4 (90.993.7)

2.5 (2.32.7)

0.19 (0.150.23)

52.2 (50.354.0)

92.4 (90.9–93.7)

Slept under LLITNs

 No

86.7 (84.3–88.9)

78.0 (76.379.6)

80.3 (78.981.6)

3.9 (3.64.3)

0.17 (0.14–0.20)

57.7 (54.9–60.3)

94.5 (93.4–95.4)

 Yes

88.6 (85.9–90.8)

72.5 (70.274.6)

77.2 (75.578.9)

3.2 (2.93.5)

0.16 (0.13–0.15)

57.4 (54.4–60.3)

93.8 (92.4–95.1)

Building material

 Totally improved

87.8 (84.290.6)

82.5 (80.884.1)

83.4 (82.084.8)

5.0 (4.65.5)

0.14 (0.110.19)

49.9 (46.353.5)

97.1 (96.397.8)

 Partially improved

89.2 (86.591.5)

71.1 (68.773.3)

76.6 (74.878.4)

3.1 (2.83.4)

0.15 (0.120.19)

57.5 (54.460.6)

93.7 (92.195.1)

 Nothing improved

85.1 (81.588.2)

60.4 (55.964.7)

72.4 (69.675.3)

2.2 (1.92.4)

0.24 (0.200.31)

67.1 (63.170.8)

81.1 (76.984.9)

Anaemia level

 Severe

97.7 (93.599.5)

38.7 (26.651.9)

78.8 (72.384.3)

1.6 (1.32.0)

0.06 (0.020.19)

77.1 (73.480.4)

88.9 (71.596.2)

 Moderate

89.3 (87.191.3)

63.7 (61.066.3)

74.2 (72.376.0)

2.5 (2.32.7)

0.17 (0.140.20)

63.0 (61.264.8)

89.6 (87.791.3)

 Mild

82.7 (78.086.8)

77.7 (75.280.0)

78.7 (76.680.8)

3.7 (3.34.2)

0.22 (0.170.28)

49.5 (46.652.5)

94.4 (93.095.6)

 Not anaemic

81.9 (76.586.5)

85.1 (83.386.8)

84.7 (83.086.3)

5.5 (4.86.3)

0.21 (0.160.28)

44.3 (41.247.5)

97.0 (96.1 - 97.7)

  1. Proportions in Bold and Italics are significantly different at 5% significance level