Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection

Table 3 Optimized subsets of the 24 SNP barcode (N = 294 samples)

	6 SNP barcode						8 SNP barcode		10 SNP barcode		12 SNP barcode
SNP	3	7	11	15	19	22	4	14	9	10	5	17
Accuracy in calling uniqueness (%)	98.5						99.5		99.8		99.9
Accuracy in determining heterozygosity (%)	78.0						79.7		83.6		89.3
% amplification success	98	97	95	95	97	96	94	93	96	97	93	90
Minor allele frequency	0.31	0.32	0.44	0.50	0.43	0.49	0.16	0.29	0.19	0.40	0.21	0.40

ISSN: 1475-2875