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Table 4 Reported non-propeller K13-mutations in Plasmodium falciparum parasites

From: K13-propeller gene polymorphisms in Plasmodium falciparum parasite population in malaria affected countries: a systematic review of prevalence and risk factors

S/n

Study/article

Amino acid change/codon position (s)

Nucleotide change

Country/region

1.

[11]

N87K, T149S, E252Q, G112E, R255K, E130G, K189N, D281V, L143P, R223K

NR

Southeast Asia

2.

[13]

I250T

NR

Myanmar

3.

[22]

K123R, N137S, T149S, K189T

123 (AAA → AGA); 137 (AAT → AGT); 149 (ACT → TCT); 189T (AAA → ACA)

Senegal

4.

[20]

A189N, A189T, T334C

189T (A → C)

189N (A → T)

334 (T → C)

Uganda

5.

[54]

E252Q

NR

Greater Mekong Sub-region

6.

[60]

K189T

AAA → ACA

India

7.

[14]

R255K, K189N

189N (AAA → AAT)

Southeast Asia

8.

[30]

N371I, E252Q

NR

Myanmar

9.

[19]

E252Q, R255K

NR

China–Myanmar boarder

10.

[38]

N11Y, K189N, E252Q, R255K, I352T, I376V

NR

China–Myanmar boarder

11.

[21]

R254L, R255K, E294G, I352T

NR

Myanmar

  1. NR, not reported