Table 5 Diagnostic test performance of clinical diagnosis, RDT, and TFM in the diagnosis of malaria with PCR as reference method
Test characteristic | Clinical diagnosis | RDT | TFM |
|---|---|---|---|
TP (PCR = 298) | 298 | 234 | 170 |
FP (PCR negative) | 209 | 15 | 2 |
TN (PCR = 253) | 44 | 237 | 251 |
FN (PCR positive) | 0 | 65 | 128 |
Sensitivity [95% CI] | 100% [99–100] | 78% [73–82] | 57% [51–63] |
Specificity [95% CI] | 17% [13–23] | 94% [90–97] | 99% [97–99] |
PPV [95% CI] | 59% [54–63] | 94% [90–96] | 99% [96–99] |
NPP [95% CI] | 100% [92–100] | 78% [73–83] | 66% [61–71] |
Accuracy [95% CI] | 62% [58–66] | 85% [82–88] | 76% [73–80] |
Kappa value [95% CI] | 0.18 [0.14–0.24] | 0.71 [0.65–0.77] | 0.54 [0.48–0.60] |
Misclassification rate (%) | 34 | 14 | 23 |