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Fig. 1 | Malaria Journal

Fig. 1

From: In vivo compartmental kinetics of Plasmodium falciparum histidine-rich protein II in the blood of humans and in BALB/c mice infected with a transgenic Plasmodium berghei parasite expressing histidine-rich protein II

Fig. 1

Kinetics of PfHRP2 following P. falciparum infection. a, b Blood was drawn from patients and fractionated into plasma and RBCs. Parasite genomic DNA clearance in a representative single patient post-treatment with artemether–lumefantrine (a, left) or atovaquone–proguanil (b, left) was quantified using TaqMan primers and probes specific for P. falciparum Pfs25. PfHRP2 protein levels were quantified in the plasma and RBCs post-treatment with artemether–lumefantrine (a, right) and atovaquone–proguanil (b, right) by ELISA. c The ratio of PfHRP2 concentration in the RBCs to plasma in each patient (n = 6) was calculated over the days post-treatment. Data are represented as mean ± SEM

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Malaria Journal

ISSN: 1475-2875

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