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Fig. 3 | Malaria Journal

Fig. 3

From: Short-term metabolic adjustments in Plasmodium falciparum counter hypoxanthine deprivation at the expense of long-term viability

Fig. 3

Effect of hypoxanthine deprivation on Plasmodium falciparum during the IDC. a Representative images of Giemsa-stained parasites at 24, 32 and 40 h in hypoxanthine-rich medium (hxan-R) and hypoxanthine-deprived medium (hxan-D). Black arrows indicate vacuole-like structures in the cytoplasm of the parasite. b Developmental-stage specific parasitaemia under the two culture conditions (hxan-R and hxan-D) at different time points. c Recovered parasite numbers shown as a percentage of parasite-infected RBCs (iRBCs) maintained in hypoxanthine-rich medium at 40 h into the IDC. The number of recovered parasites is calculated 24 h after the transfer of the deprived parasites to the rich medium. ET, early trophozoite; hxan-D, hypoxanthine-deprived; hxan-R, hypoxanthine-rich; LT, late trophozoite; R, ring; S, schizont

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