Skip to main content

Table 1 Model-predicted changes in parasite-infected RBC metabolism

From: Short-term metabolic adjustments in Plasmodium falciparum counter hypoxanthine deprivation at the expense of long-term viability

Metabolic pathway Number of metabolic reactions
Hypoxanthine-rich medium (90 µM) Hypoxanthine-deprived medium (0.5 µM)
Phospholipid 7 8
Haem synthesis 7 7
Pentose phosphate pathway 1 1
Haem degradation 3 3
  1. Statistically significant reactions, between simulations of uninfected and parasite-infected erythrocyte metabolism, computed using Student’s t-test and a criterion of p < 0.01