Fig. 3
From: Structure–activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines

General procedure for preparation of thieno[2,3-b]pyridines 2–4. Reagents and conditions: (i) ethanol, piperidine, reflux, 3–6 h; (ii) 10% KOH, DMF, 30 min (iii) 10% KOH, DMF, 1–5 h