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Table 1 Risk predictors of P. vivax (A) infection prevalence, (B) new infection, and (C) infection density by qPCR detection

From: Molecular epidemiology of residual Plasmodium vivax transmission in a paediatric cohort in Solomon Islands

  Overall P. vivax prevalence (%) (A) Prevalence (B) New P. vivax infection (C) P. vivax density
ORa aOR 95% CI IRRa aIRR 95% CI Coeff.a aCoeff. 95% CI
Age
 Linear n/a 1.16* 1.18 [1.13, 1.23] 1.18* 1.21 [1.16, 1.25] n/a
 Quadratic n/a n/a − 0.01* 0.00 [− 0.01, − 0.002]
    p–value < 0.001   p-value < 0.001   p-value < 0.001
Villages (for details refer to Additional file 10) 1.2–47.4 0.13–8.32 0.18–6.86 [0.02, 17.52] 0.07–4.96 0.11–6.18 [0.01, 12.42] − 0.59–0.67 − 0.66–0.35 [− 0.95, 0.98]
   p-value < 0.001   p-value < 0.001   p-value < 0.001
ACD follow-up timepoint (for details refer to Additional file 10) 9.0–16.2 0.72–1.39 0.69–1.46 [0.50, 1.86] 0.46–0.95 0.45–0.93 [0.32, 1.28] − 0.25–0.14 − 0.47–0.15 [− 0.73, 0.38]
   p-value < 0.001   p-value < 0.001   p-value < 0.001
LLIN usage (per 10% increase in use) n/a 0.94* 0.89 [0.82, 0.97] 0.97 n/a 0.03 n/a
   p-value = 0.006       
molFOB of P. vivax n/a n/a n/a 0.02 0.02 [0.001, 0.04]
         p-value = 0.036
Previous antimalarial record (1 year before only) 20.9 2.61* 2.03 [1.45, 2.83] 1.95* 1.52 [1.16, 1.98] 0.45* 0.24 [0.07, 0.41]
   p-value < 0.001   p-v`alue = 0.002   p-value = 0.005
G6PD deficient 16.9 1.56* 1.77 [1.16, 2.70] 1.42 1.51 [1.05, 2.18] −0.11 n/a
   p-value = 0.008   p-value = 0.026    
α-Thalassaemia mutationb 14.2 1.56* n/a 1.58* 1.42 [1.10, 1.84] −0.06 n/a
      p-value = 0.007    
Febrile 15.1 1.21 n/a n/a 0.62* 0.51 [0.10, 0.92]
        p-value = 0.014
  1. Statistical analyses used were: (A) logistic regression method for prevalence analysis, (B) negative binomial regression method for incidences of new infection analysis, and (C) linear regression method for infection density analysis
  2. OR odds ratio, aOR adjusted odds ratio, 95% CI 95% confidence intervals for adjusted estimates, IRR incidence rate ratio, aIRR adjusted incidence rate ratio, Coeff. coefficient, aCoeff. adjusted coefficient
  3. Data with asterisk (*) denotes significance (p-value < 0.05)
  4. aUnivariate data
  5. bChildren with at least one mutated α-thalassaemia gene