Table 1 Prevalence of Pfdhfr and Pfdhps SNPs in Plasmodium falciparum isolates from Bioko Island, Equatorial Guinea
Gene | SNP | Wild type | Mutation | Mixed type |
|---|---|---|---|---|
n (%, 95% CI) | n (%, 95% CI) | n (%, 95% CI) | ||
Pfdhfr (n = 167) | 51 | 3 (1.80, − 0.22 to 3.82) | 163 (97.60, 95.28 to 99.92) | 1 (0.60, − 0.57 to 1.77) |
59 | 12 (7.19, 3.27 to 11.11) | 146 (87.43, 82.4 to 92.46) | 9 (5.39, 1.97 to 8.81) | |
108 | 3 (1.80, − 0.22 to 3.82) | 162 (97.01, 94.43 to 99.59) | 2 (1.20, − 0.45 to 2.85) | |
Pfdhps (n = 158) | 436 | 115 (72.78, 65.84 to 79.72) | 32 (20.25, 13.98 to 26.52) | 11 (6.96, 2.99 to 10.93) |
437 | 12 (7.59, 3.46 to 11.72) | 143 (90.51, 85.94 to 95.08) | 3 (1.90, − 0.23 to 4.03) | |
540 | 146 (92.41, 88.28 to 96.54) | 8 (5.06, 1.64 to 8.48) | 4 (2.53, 0.08 to 4.98) | |
581 | 152 (96.20, 93.22 to 99.18) | 1 (0.63, − 0.6 to 1.86) | 5 (3.16, 0.43 to 5.89) | |
613 | 153 (96.84, 94.11 to 99.57) | 5 (3.16, 0.43 to 5.89) | 0 (0.00) |