Table 3 Prevalence of Pfdhfr and Pfdhps allele combinations in Plasmodium falciparum isolates from Bioko Island, Equatorial Guinea
Gene | Category | Haplotype | n (%, 95% CI) |
|---|---|---|---|
Pfdhfr/Pfdhps (n = 130) | Wild type | CNCSI-SAKAA | 1 (0.77, − 0.73 to 2.27) |
Single mutant | CNCSI-SGKAA | 1 (0.77, − 0.73 to 2.27) | |
Triple mutant | CICNI-SGKAA | 6 (4.62, 1.01 to 8.23) | |
CIRNI-SAKAA | 1 (0.77, − 0.73 to 2.27) | ||
Quadruple mutant | CICNI-SGEAA | 1 (0.77, − 0.73 to 2.27) | |
CIRNI-AAKAA | 7 (5.38, 1.5 to 9.26) | ||
CIRNI-SGKAA | 85 (65.38, 57.2 to 73.56) | ||
CIRNI-AGKAA | 16 (12.31, 6.66 to 17.96) | ||
Quintuple mutant | CIRNI-SGEAA | 6 (4.62, 1.01 to 8.23) | |
CIRNI-SGKAS | 1 (0.77, − 0.73 to 2.27) | ||
Sextuple mutant | CIRNI-AGKAS | 4 (3.08, 0.11 to 6.05) | |
CIRNI-SGEGA | 1 (0.77, − 0.73 to 2.27) |