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Table 5 Measurement of 12-h mortality, 24-h mortality and blood feeding inhibition compared between WHO Tunnel test and I-ACT for sampled Olyset® nets through 3 years of field use

From: Comparing the new Ifakara Ambient Chamber Test with WHO cone and tunnel tests for bioefficacy and non-inferiority testing of insecticide-treated nets

 

Geometric mean (95% confidence interval)

Odds ratio

95% confidence interval

p-value

Year 1

Year 2

Year 3

Overall

Olyset

 % 12 h mortality

  Tunnel test

44.2 (36.5–53.5)

55.1 (47.8–63.5)

50.3 (42.2–60.1)

49.5 (44.9–54.6)

1

  

  I-ACT

73.2 (68.3–78.5)

56.1 (48.65–64.7)

63.4 (57.11–70.3)

64.1 (60.1–68.3)

1.7

1.6–1.8

< 0.0001

 % 24 h mortality

  Tunnel test

61.4 (52.2–72.3)

64.7 (57.2–73.1)

67.7 (61.9–74.0)

64.4 (59.8–69.4)

1

  

  I-ACT

83.8 (78.9–89.1)

65.20 (59.56–71.4)

64.9 (59.15–71.2)

71.2 (67.7–74.9)

1.3

1.2–1.4

< 0.0001

 % feeding inhibition

  Tunnel test

85.3 (80.0–90.8)

91.9 (89.2–94.7)

90 (84.8–95.6)

88.9 (86.2–91.7)

1

  

  I-ACT

99.6 (99.3–100)

98 (95.6–99.9)

91.3 (87.2–95.8)

96.4 (94.7–98.1)

3.6

3.1–4.2

< 0.0001