From: Safety of primaquine in infants with Plasmodium vivax malaria in Papua, Indonesia
Patient number | Age | Sex | Ethnicity | Species | Initial Hb (g/dL) | Lowest F/U Hb (g/dL) | Days between presentation and lowest F/U Hb | Days between presentation and death | Schizontocidal drug used | Primaquine dose | Other clinical diagnoses assigned between presentation and death |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 1 m | M | HP | Pv | 7.1 | 3.4 | 14 | 20 | IV artesunate/DHA + PIP | Nil | Gastroenteritis Malnutrition Dehydration Pulmonary tuberculosis |
2 | 1 m | M | HP | Mix | 2.3 | – | – | 4 | IV artesunate | Nil | Bacterial sepsis of newborn Neonatal jaundice Late metabolic acidosis of newborn Cerebral malaria |
3 | 1 m | F | HP | Pv | – | 9.3 | 27 | 27 | DHA + PIP | Nil | Oral candidiasis Staphylococcal scalded skin syndrome Stevens-Johnsons syndrome Hypoglycaemia |
4 | 2 m | M | HP | Pv | 6.3 | – | – | 13 | IV artesunate/DHA + PIP | Nil | Septic shock Respiratory distress syndrome of newborn Hypoalbuminaemia |
5 | 2 m | F | HP | Mix | – | – | – | 27 | DHA + PIP | Nil | Bacterial meningitis Acute upper respiratory tract infection |
6 | 2 m | M | HP | Pv | – | 9.8 | 20 | 25 | IV artesunate/DHA + PIP | Nil | Bronchopneumonia |
7 | 4 m | M | HP | Pv | 8.3 | 6.8 | 24 | 26 | PO quinine | Nil | Gastroenteritis Acidosis Meningitis |
8 | 4 m | F | HP | Pv | 11.1 | 11.2 | 6 | 16 | DHA + PIP | Nil | HIV Pulmonary tuberculosis Marasmus Candidiasis |
9 | 4 m | M | HP | Pv | – | 9.7 | 3 | 4 | DHA + PIP | Nil | Bacterial meningitis |
10 | 4 m | F | HP | Pv | – | 8 | 20 | 26 | DHA + PIP | Nil | Bronchopneumonia |
11 | 5 m | M | HP | Pv | 13 | – | – | 12 | IV artesunate/DHA + PIP | Nil | Bronchopneumonia Septic shock |
12 | 6 m | F | HP | Pv | 3.5 | – | – | 4 | IV/PO quinine | Nil | Bronchopneumonia Exfoliative dermatitis |
13 | 6 m | F | HP | Mix | 2.1 | – | – | 3 | IV artesunate/DHA + PIP | Nil | Bronchopneumonia |
14 | 8 m | F | HP | Pv | 9.6 | – | – | 12 | IV artesunate/DHA + PIP | Nil | Tuberculous meningitis Septic shock Conjunctivitis |
15 | 10 m | M | NP | Pv | 7.2 | – | – | 3 | IV artesunate/DHA + PIP | High dose | Tuberculosis of skin and subcutaneous tissue |
16 | 10 m | F | LP | Pv | – | – | – | 10 | DHA + PIP | Nil | Measles Gastroenteritis and colitis Bronchopneumonia |
17 | 12 m | F | HP | Pv | 6.4 | 4.6 | 3 | 9 | PO quinine | High dose | Bronchopneumonia |
18 | 12 m | M | HP | Pv | 8.7 | 4.3 | 23 | 24 | DHA + PIP | Nil | Gastroenteritis Dehydration Septic shock Acidosis Respiratory failure Febrile convulsion |
19 | 12 m | F | HP | Pv | 8.9 | – | – | 9 | DHA + PIP | Nil | Pneumonia Septic shock |
20 | 12 m | M | HP | Pv | 7.9 | – | – | 7 | DHA + PIP | Low dose | Gastroenteritis Malnutrition Dehydration Acidosis |