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Fig. 1 | Malaria Journal

Fig. 1

From: Population pharmacokinetics and pharmacodynamics of the artesunate–mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children

Fig. 1

Prediction corrected visual predictive check of the final model of a artesunate and b dihydroartemisinin. Open circles represent prediction corrected observed plasma concentration; black solid and dashed lines the median and PI90% of the observed data; shaded magenta and grey surfaces the model predicted 90% confidence interval of the simulated median and PI90%, respectively; horizontal black lines are the LOQ of AS (0.005 nmol/mL) and DHA (0.005 nmol/mL). The lower panels show the fraction of observed (open circles) with the PI95% of the simulated (shaded magenta surface) BQL data

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Malaria Journal

ISSN: 1475-2875

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