Age-dependent increase in antibodies that inhibit Plasmodium falciparum adhesion to a subset of endothelial receptors

Table 1 Study population providing plasma samples

Receptor	n	Number of plasma samples/child Mean (range)	Median age (months)^a	Number of previous infections Mean (SD)^a
CD36	129	1.6 (1–3)	21.0	3.3 (2.6)
Cell. Fibronectin	105	1.9 (1–2)	18.3	2.9 (2.0)
ICAM-1	137	1.4 (1–3)	14.7	2.8 (2.1)
Integrin α_vβ₃	110	1.7 (1–4)	22.0	2.7 (2.1)
Integrin α₃β₁	120	1.8 (1–5)	24.2	2.6 (1.9)
Integrin α₅β₁	129	2.1 (1–4)	28.6	2.8 (2.2)
JAM-B	138	2.0 (1–3)	17.8	2.7 (1.9)
Laminin	112	1.9 (1–4)	18.4	2.7 (2.1)
PECAM-1	166	1.9 (1–4)	18.3	2.7 (2.0)
P-selectin	82	1.3 (1–3)	23.8	2.4 (1.8)
IE surface (flow)	106	2.0 (1–2)	18.4	2.8 (2.0)

^aFor children providing multiple samples, age and number of previous infections at each time point were included

ISSN: 1475-2875