Table 2 Temperature persistence and parasite clearance
Characteristics | Treatment outcome | p-value | |
|---|---|---|---|
Artefan® arm (n = 78) | Coartem® arm (n = 75) | ||
Temperature persistence (temperature ≥ 37.5 °C) | |||
On day 0 | 66 (84.6%) | 61 (81.3%) | 0.60 |
On day 3 | 1 (1.3%) | 0 (0.0%) | 0.54 |
On day 7 | 2 (2.9%) | 0 (0.0%) | 0.25 |
On day 14 | 2 (2.9%) | 0 (0.0%) | 0.26 |
On day 21 | 1 (1.6%) | 0 (0.0%) | 0.51 |
On day 28 | 3 (5%) | 1 (1.7%) | 0.31 |
Parasite clearance | |||
Smear positive on day 3 | 0 | 0 | |
Smear positive on day 7 | 0 | 0 | |
Smear positive on day 14 | 0 (0.0%) | 1 (1.1%) | 0.71 |
Smear positive on day 21 | 6 (7.7%) | 10 (13.3%) | 0.42 |
Smear positive on day 28 | 6 (7.7%) | 6 (8%) | 0.97 |
Mean hemoglobin concentration (SD) | |||
Day 3 | 8.9 (1.5) | 8.8 (1.4) | 0.96 |
Day 7 | 9.0 (1.4) | 9.1 (1.5) | 0.73 |
Day 14 | 9.8 (1.3) | 9.6 (1.3) | 0.43 |
Day 21 | 10 (1.4) | 9.8 (1.4) | 0.97 |
Day 28 | 10.3 (1.4) | 10.4 (1.3) | 0.74 |