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Table 3 Malaria incidence rates for the intervention arms for some background variables

From: Long-lasting insecticidal nets and indoor residual spraying may not be sufficient to eliminate malaria in a low malaria incidence area: results from a cluster randomized controlled trial in Ethiopia

 

Intervention arm

IRS + LLIN

LLIN

IRS

Malaria episodes

Person years

Incidence (95% CI)

Malaria episodes

Person years

Incidence (95% CI)

Malaria episodes

Person years

Incidence (95% CI)

Malaria episodes

 First episode (cases)

287

18,376

15.6 (13.9–17.5)

254

16,972

15.0 (13.2–16.8)

261

16,869

15.5 (13.7–17.4)

 All malaria episodes

321

18,713

17.2 (15.3–19.1)

278

17,244

16.1 (14.3–18.1)

291

17,153

17.0 (15.1–19.0)

 P. falciparum

180

18,713

9.6 (8.2–11.0)

173

17,243

10.0 (8.5–11.5)

153

17,154

8.9 (7.5–10.3)

 P. vivax

86

18,713

4.6 (3.6–5.6)

69

17,243

4.0 (3.1–4.9)

68

17,154

4.0 (3.0–4.9)

 Mixed (Pf + Pv)

57

18,713

3.0 (2.3–3.8)

36

17,243

2.1 (1.4–2.8)

68

17,154

4.0 (3.0–4.9)

Age

 0–5 years

79

3252

24.3 (18.9–29.6)

83

3105

26.7 (21.4–33.0)

54

2951

18.3 (13.9–23.7)

 6–15 years

103

5975

17.2 (14.1–20.8)

91

5933

15.3 (12.2–18.5)

83

5840

14.2 (11.2–17.3)

 Older than 16 years

139

9481

14.7 (12.4–17.3)

104

8206

12.7 (10.4–15.3)

154

8360

18.4 (15.5–21.3)

Time period

 Week 1–26

83

4071

21.1 (17.0–26.0)

56

3738

15.0 (11.1–19.0)

75

3839

19.5 (15.1–24.0)

 Week 26–52

76

4114

18.5 (14.3–22.6)

61

3765

16.2 (12.1–20.3)

54

3789

14.3 (10.5–18.1)

 Week 53–79

62

4091

15.2 (11.4–19.0)

59

3786

15.6 (11.6–20.0)

64

3682

17.4 (13.1–21.6)

 Weeks 79–121

100

6437

15.5 (12.5–18.6)

102

5954

17.1 (13.8–20.5)

98

5845

16.8 (13.5–20.1)

Clustering

 Cluster area

104

2720

38.2 (31.4–46.1)

126

2735

46.1 (38.5–54.7)

169

3513

48.1 (41.2–55.8)

 Non-cluster area

217

15,993

13.6 (11.9–15.5)

152

14,509

10.5 (8.9–12.2)

122

13,639

8.9 (7.5–10.6)

LLIN use

 Over 50%

13

551

23.6 (13.1–39.3)

13

449

29 (16.1–48.3)

0

9

0.0

 25–49%

80

5618

14.2 (11.3–17.6)

72

5224

13.8 (10.9–17.3)

7

135

52 (22.7–102.6)

 0–24%

228

12,543

18.2 (15.9–20.7)

193

11,571

16.7 (14.5–19.2)

284

17,010

16.7 (14.8–18.7)

 

Control

Total

Malaria episodes

Person years

Incidence (95% CI)

Malaria episodes

Person years

Incidence (95% CI)

Malaria episodes

 First episode (cases)

257

18,441

13.9 (12.3–15.7)

1059

70,658

15.0 (14.1–15.9)

 All malaria episodes

293

18,752

15.6 (13.9–17.5)

1183

71862

16.5 (15.5–17.4)

 P. falciparum

146

18,752

7.8 (6.5–9.0)

652

71,862

9.1 (8.4–9.8)

 P. vivax

76

18,752

4.1 (3.1–5.0)

299

71,862

4.2 (3.7–4.6)

 Mixed (Pf + Pv)

71

18,752

3.8 (2.9–4.7)

232

71,862

3.3 (2.8–3.6)

Age

 0–5 years

54

3429

15.7 (11.6–20.0)

270

12,742

21.2 (18.6–23.7)

 6–15 years

98

5979

16.4 (13.2–20.0)

375

23,727

15.8 (14.2–17.4)

 Older than 16 years

141

9344

15.1 (12.6–17.6)

538

35,393

15.2 (13.9–16.5)

Time period

 Week 1–26

78

4107

19.0 (14.8–23.2)

292

15,755

18.5 (16.4–20.7)

 Week 26–52

60

4112

15.0 (11.0–18.3)

251

15,780

16.0 (14.0–18.0)

 Week 53–79

71

4 087

17.4 (13.3–21.4)

256

15,646

16.4 (14.4–18.4)

 Weeks 79–121

84

6445

13.0 (10.3–16.0)

384

24,681

15.6 (14.0–17.1)

Clustering

 Cluster area

156

3,704

42.1 (35.9–49.1)

484

12,672

38.2 (34.9–41.7)

 Non-cluster area

137

15,049

9.1 (7.6–10.7)

575

59,190

9.7 (8.9–10.5)

LLIN use

 Over 50%

0

0

0.0

26

1009

25.8 (17.2–37.2)

 25–49%

3

94

32 (8.1–86.9)

162

11,071

14.6 (12.5–17.0)

 0–24%

290

18,658

15.5 (13.8–17.4)

995

59,782

16.6 (15.6–17.7)

  1. LLIN long-lasting insecticidal nets; IRS indoor residual spraying