Study population/molecular protocol | True positive | False positivea | True negative | False negative | Sensitivity (CI 95%) | Specificity (CI 95%) |
---|---|---|---|---|---|---|
Clinical malaria suspects | ||||||
Nested-PCR | 36 | 0 | 70 | 4 | 90% (0.76–0.97) | 100% (0.95–1.0) |
R-qPCR | 37 | 1 | 70 | 2 | 95% (0.83–0.99) | 99% (0.92–1.0) |
NR-cPCR | 34 | 0 | 70 | 6 | 85% (0.70–0.94) | 100% (0.95–1.0) |
NR-qPCR | 36 | 1 | 70 | 3 | 92% (0.79–0.98) | 99% (0.92–1.0) |
Subclinical malaria suspects | ||||||
Nested-PCR | 16 | 1 | 232 | 75 | 18% (0.10–0.27) | 100% (0.98–1.0) |
R-qPCR | 67 | 2 | 232 | 23 | 74% (0.64–0.83) | 99% (0.97–1.0) |
NR-cPCR | 42 | 0 | 232 | 50 | 46% (0.35–0.56) | 100% (0.98–1.0) |
NR-qPCR | 72 | 17 | 232 | 3 | 96% (0.89–0.99) | 93% (0.89–0.96) |