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Table 1 Estimates of nucleotide diversity, natural selection, haplotype diversity and neutrality indices of pkmsp7

From: Plasmodium knowlesi clinical isolates from Malaysia show extensive diversity and strong differential selection pressure at the merozoite surface protein 7D (MSP7D)

Region No. samples SNPs No. haplotype Diversity ± SD dN − dS Codon-based z test Taj D Fu and Li’s D* Fu and Li’s F*
Haplotype Nucleotide
Full-length 36 203 34 0.998 ± 0.007 0.052 ± 0.002 − 2.0 P > 0.1 0.295 0.190 0.270
5′ region 28 30 0.992 ± 0.009 0.010 ± 0.001 − 3.0 P > 0.1 − 1.25 − 2.24 − 2.26
Central region 151 32 0.995 ± 0.008 0.1495 ± 0.006 1.84 P < 0.05 0.673 0.896 0.973
3′ region 32 30 0.990 ± 0.010 0.017 ± 0.0007 − 2.68 P < 0.01 − 0.275 − 1.027 − 0.917
  1. SNPs single nucleotide polymorphisms, SD standard deviation