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Fig. 5 | Malaria Journal

Fig. 5

From: Comparing sequence and structure of falcipains and human homologs at prodomain and catalytic active site for malarial peptide based inhibitor design

Fig. 5

A phylogenetic tree of plasmodial and human FP-3, and FP-3 homologs prodomain-catalytic protein sequences using MEGA5.2.2. The evolutionary history was inferred by using the Maximum Likelihood method based on the Whelan and Goldman model (WAG) model with a γ discrete distribution (+G) parameter of 2.4 and an evolutionary invariable ([+I]) of 0.1. All positions with gaps were completely removed (100% deletion) and bootstrap value set at 1000. The scale bar represents the number of amino acid substitutions per site. Toxoplasma gondii CAT-L is used as the outgroup

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