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Table 1 Details of all protein sequences retrieved from PlasmoDB and NCBI databases

From: Comparing sequence and structure of falcipains and human homologs at prodomain and catalytic active site for malarial peptide based inhibitor design

Source organism

Host

Accession number

Common name (abbreviation)

aa

% SI

P. falciparum (Pf)

Human

PF3D7_1115700

Falcipain-2 (FP-2)

484

QS

PF3D7_1115400

Falcipain-3 (FP-3)

492

QS

P. vivax (Pv)

PVX_091415

Vivapain-2 (VP-2)

487

56a

PVX_091410

Vivapain-3 (VP-3)

493

55b

P. knowlesi (Pk)

Human/monkey

PKH_091250

Knowlesipain-2 (KP-2)

495

53a

PVX-091260

Knowlesipain-3 (KP-3)

479

58b

P. yoelii (Py)

Rodents

PY00783

Yoelipain-2 (YP-2)

472

47a

P. chabaudi (Pc)

PCHAS_091190

Chabaupain-2 (CP-2)

471

48b

P. berghei (Pb)

PBANKA_093240

Berghepain-2 (BP-2)

470

50a

H. sapiens

–

NP_000387.1

Cathepsin-K (Cat-K)

329

34a

AAA66974.1

Cathepsin-L (Cat-L)

333

33a

AAC37592.1

Cathepsin-S (Cat-S)

331

32a

  1. Percentage sequence identity (SI) is calculated based on the partial zymogen of query sequence (QS) and that of corresponding homolog
  2. aFP-2 homolog, bFP-3 homolog