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Table 2 Homology model quality validation scores of partial zymogen complexes using different assessment tools

From: Comparing sequence and structure of falcipains and human homologs at prodomain and catalytic active site for malarial peptide based inhibitor design

Protein

Z-DOPE

Verify3D

ProSA

QMEAN

RAMACHANDRAN (%)

Favoured

Allowed

Disallowed

FP-2

− 1.05

78.48

− 8.27

0.69

88.90

10.50

0.60

FP-3

− 0.94

84.64

− 7.84

0.67

89.70

10.30

0.00

VP-2

− 0.64

81.27

− 6.94

0.62

85.40

13.90

0.70

VP-3

− 0.74

79.58

− 7.31

0.70

88.60

11.40

0.00

KP-2

− 0.63

85.89

− 7.23

0.62

89.30

9.70

1.00

KP-3

− 0.92

90.63

− 7.88

0.63

86.10

13.90

0.00

BP-2

− 0.62

86.85

− 7.75

0.63

86.60

12.40

1.00

CP-2

− 0.60

84.45

− 7.02

0.63

83.90

13.80

2.30

YP-2

− 0.42

75.54

− 7.28

0.62

84.90

14.40

0.70

Cat-L

− 1.47

87.38

− 7.94

0.87

89.80

9.80

0.40

Cat-S

− 1.61

85.39

− 8.57

0.79

89.20

10.40

0.20

1BY8

*

85.16

− 8.62

0.78

65.80

34.20

0.00

2O6X

*

94.77

− 7.00

0.77

90.50

9.50

0.00

2OUL

*

98.13

− 7.90

0.75

88.10

11.20

0.70

3BWK

*

93.51

− 7.35

0.65

86.10

13.30

0.60

  1. * Template