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Fig. 2 | Malaria Journal

Fig. 2

From: Primaquine–quinoxaline 1,4-di-N-oxide hybrids with action on the exo-erythrocytic forms of Plasmodium induce their effect by the production of reactive oxygen species

Fig. 2

6a and 6b PQ–QdNO hybrids induce production of ROS in HepG2-CD81 alone or infected with P. yoelii 17XNL. Line graphs (ac) show the percentage of DCF positive HepG2-CD81 cells infected with P. yoelii 17XNL or uninfected and treated with hybrids 6a (a), 6b (b) and primaquine (c). The data are expressed as the average of three independent experiments. **p < 0.01 shows a statistically significant comparison between infected and uninfected groups. #p < 0.05, ##p < 0.01, ###p < 0.001 show significant intra-group differences

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