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Fig. 4 | Malaria Journal

Fig. 4

From: Primaquine–quinoxaline 1,4-di-N-oxide hybrids with action on the exo-erythrocytic forms of Plasmodium induce their effect by the production of reactive oxygen species

Fig. 4

Mitochondrial membrane potential (DYm) of HepG2-CD81 was not disturbed by infection P. yoelii 17XNL or treatment with 6a and 6b PQ–QdNO hybrids. Bar graphs (a, b) show the percentage of DiOC6 (3) positive HepG2-CD81 cells for in the uninfected groups (a) or infected with P. yoelii 17XNL (b) and treated with 6a, 6b hybrids, and primaquine. The data are expressed as the mean of three independent experiments ± SD. *p < 0.05 and **p < 0.01 shows statistically significant differences compared to the control group

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