Coefficient | Value |
---|
β
final
| 0.477 |
λ
| 5.354 |
α
| 0.827 |
σ | 0.215 |
β
Initial
| 0.432 |
- βfinal represents the value of the scaling parameter, β, after the second model-fitting (to the literature review data) and βInitial represents the value of β after the first model fitting (to the DHS Program data), which is not used in the final model fit. The parameter λ controls the rate of decline of the proportion of MAF within malaria-positive fevers with increasing PfPR0–5. The parameter α controls the minimum proportion of malaria-positive fevers in a population that can be due to malaria. The parameter σ is the standard deviation/observational noise parameter. Full details of model fitting and parameter optimisation can be found in the Additional file 6