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Table 4 Association between antibody levels and the risk of malaria infection from 6 to 18 months of age (multivariate analysis with logistic mixed model)

From: Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort

Variables OR p CI (95%)
IgG1 to AMA1 1.07 0.039 [1.00,1.15]
 Placental malaria 2.03 0.043 [1.02,4.06]
 Environmental risk 1.22 < 0.001 [1.16,1.29]
 Nutritional status 1.36 0.297 [0.76,2.46]
 Age (months)a
  9 1.97 0.004 [1.25,3.11]
  12 4.91 < 0.001 [3.08,7.81]
  15 6.90 < 0.001 [4.31,11.05]
 Ethnic groupb
  Fon 0.96 0.926 [0.46,2.01]
  Others 0.51 0.037 [0.27,0.96]
IgG3 to AMA1 1.09 0.021 [1.01,1.18]
 Placental malaria 2.03 0.045 [1.01,4.07]
 Environmental risk 1.22 < 0.001 [1.16,1.29]
 Nutrition status 1.48 0.193 [0.81,2.69]
 Age (months)
  9 1.89 0.006 [1.20,2.99]
  12 5.10 < 0.001 [3.20,8.12]
  15 7.18 < 0.001 [4.49,11.50]
 Ethnic group
  Fon 0.90 0.790 [0.43,1.88]
  Others 0.49 0.031 [0.26,0.93]
  1. Significant p values (p < 0.05) are mentioned in italics
  2. OR: odds ratio; OR > 1: variables associated with higher risk of malarial infection from 6 to 18 months of age; OR < 1: variables associated with lower risk of malarial infection from 6 to 18 months of age; p: p-value; CI: confidence interval
  3. a6, 9, 12 and 15 months quantifications were considered in analyses and 6 month quantification was used as the age of reference
  4. bEthnic groups were Tori, Fon and other less represented ethnic groups (Aïzo, Yoruba, …). Tori was used as the reference group in the analyses