Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort

Table 4 Association between antibody levels and the risk of malaria infection from 6 to 18 months of age (multivariate analysis with logistic mixed model)

Variables	OR	p	CI (95%)
IgG1 to AMA1	1.07	0.039	[1.00,1.15]
Placental malaria	2.03	0.043	[1.02,4.06]
Environmental risk	1.22	< 0.001	[1.16,1.29]
Nutritional status	1.36	0.297	[0.76,2.46]
Age (months)^a
9	1.97	0.004	[1.25,3.11]
12	4.91	< 0.001	[3.08,7.81]
15	6.90	< 0.001	[4.31,11.05]
Ethnic group^b
Fon	0.96	0.926	[0.46,2.01]
Others	0.51	0.037	[0.27,0.96]
IgG3 to AMA1	1.09	0.021	[1.01,1.18]
Placental malaria	2.03	0.045	[1.01,4.07]
Environmental risk	1.22	< 0.001	[1.16,1.29]
Nutrition status	1.48	0.193	[0.81,2.69]
Age (months)
9	1.89	0.006	[1.20,2.99]
12	5.10	< 0.001	[3.20,8.12]
15	7.18	< 0.001	[4.49,11.50]
Ethnic group
Fon	0.90	0.790	[0.43,1.88]
Others	0.49	0.031	[0.26,0.93]

Significant p values (p < 0.05) are mentioned in italics
OR: odds ratio; OR > 1: variables associated with higher risk of malarial infection from 6 to 18 months of age; OR < 1: variables associated with lower risk of malarial infection from 6 to 18 months of age; p: p-value; CI: confidence interval
^a6, 9, 12 and 15 months quantifications were considered in analyses and 6 month quantification was used as the age of reference
^bEthnic groups were Tori, Fon and other less represented ethnic groups (Aïzo, Yoruba, …). Tori was used as the reference group in the analyses

ISSN: 1475-2875