Therapeutic efficacy of artesunate–amodiaquine and artemether–lumefantrine combinations for uncomplicated malaria in 10 sentinel sites across Ghana: 2015–2017

Table 3 Day 28 PCR-uncorrected study endpoints for children enrolled

Antimalarial drug	Treatment outcome	Sentinel site										Total
Antimalarial drug	Treatment outcome	WRH	NWMH	YMH	SMH	BMH	BGH	HMH	TAGH	LEKMH	EWP	Total
AS–AQ		n = 51	n = 55	n = 0	n = 54	n = 63	n = 62	n = 61	n = 61	n = 23	n = 62	N = 492
	ETF	0	1	–	0	0	0	0	0	0	0	1
	LCF	0	0	–	0	0	0	0	0	0	0	0
	LPF	0	0	–	0	1	1	0	0	0	4	6
	ACPR	45	54	–	51	62	58	58	60	20	58	466
	LFU	5	0	–	3	0	3	3	1	3	0	18
	WTH	1	0	–	0	0	0	0	0	0	0	1

Antimalarial drug	Treatment outcome	Sentinel site										Total
Antimalarial drug	Treatment outcome	WRH	NWMH	YMH	SMH	BMH	BGH	HMH	TAGH	LEKMH	EWP	Total
AL		n = 0	n = 58	n = 60	n = 43	n = 63	n = 63	n = 60	n = 58	n = 0	n = 67	N = 472
	ETF	–	0	0	1	0	0	0	2	–	0	3
	LCF	–	0	0	0	1	1	0	0	–	0	2
	LPF	–	5	3	3	3	1	0	12	–	9	36
	ACPR	–	53	54	39	59	57	47	42	–	54	405
	LFU	–	0	0	0	0	2	13	2	–	1	18
	WTH	–	0	3	0	0	2	0	0	–	3	8

WRH Wa Regional Hospital, NWMH Navrongo War Memorial Hospital, YMH Yendi Municipal Hospital, SMH Sunyani Municipal Hospital, BMH Bekwai Municipal Hospital, BGH Begoro Government Hospital, HMH Hohoe Municipal Hospital, TAGH Tarkwa Apinto Government Hospital, LEKMH Ledzokuku-Krowor Municipal Hospital, EWP Ewim Polyclinic, ETF early treatment failure, LCF late clinical failure, LPF late parasitological failure, ACPR adequate clinical and parasitological response, LFU loss to follow-up, WTH withdrawn

ISSN: 1475-2875